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1.
公开(公告)号:US20130277218A1
公开(公告)日:2013-10-24
申请号:US13876813
申请日:2011-10-03
申请人: Jared M. Mudrik , Hao Yang , Aaron R. Wheeler
发明人: Jared M. Mudrik , Hao Yang , Aaron R. Wheeler
CPC分类号: G01N1/34 , B01L3/502753 , B01L3/502792 , B01L2200/0631 , B01L2300/0636 , B01L2300/0816 , B01L2300/089 , B01L2400/0427 , B81B1/00 , C12N15/1003 , C12N15/1006
摘要: Devices and methods are provided for performing droplet-based solid phase processing steps on a digital microfluidic device. A solid phase material, which may be a porous solid phase material such as a porous polymer monolith is formed or located on a digital microfluidic element. The solid phase may be formed by an in-situ method in which the digital microfluidic array is actuated to transport a droplet of solid phase pre-cursor solution to a selected element on the array, and subsequently processed to form a solid phase on the array element. The integration of a solid phase material with a digital microfluidic array enables a wide range of applications including solid phase extraction and sample concentration.
摘要翻译: 提供了用于在数字微流体装置上执行基于液滴的固相处理步骤的装置和方法。 可以形成或位于数字微流体元件上的固相材料,其可以是多孔固相材料,例如多孔聚合物整料。 固相可以通过原位方法形成,其中数字微流体阵列被致动以将液相的固相前体溶液输送到阵列上的所选元素,并且随后被处理以在阵列上形成固相 元件。 固相材料与数字微流体阵列的集成使得能够广泛应用于固相萃取和样品浓缩。
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2.
公开(公告)号:US09476811B2
公开(公告)日:2016-10-25
申请号:US13876813
申请日:2011-10-03
申请人: Jared M. Mudrik , Hao Yang , Aaron R. Wheeler
发明人: Jared M. Mudrik , Hao Yang , Aaron R. Wheeler
IPC分类号: G01N27/453 , G01N1/34 , C12N15/10 , B81B1/00 , B01L3/00
CPC分类号: G01N1/34 , B01L3/502753 , B01L3/502792 , B01L2200/0631 , B01L2300/0636 , B01L2300/0816 , B01L2300/089 , B01L2400/0427 , B81B1/00 , C12N15/1003 , C12N15/1006
摘要: Devices and methods are provided for performing droplet-based solid phase processing steps on a digital microfluidic device. A solid phase material, which may be a porous solid phase material such as a porous polymer monolith is formed or located on a digital microfluidic element. The solid phase may be formed by an in-situ method in which the digital microfluidic array is actuated to transport a droplet of solid phase pre-cursor solution to a selected element on the array, and subsequently processed to form a solid phase on the array element. The integration of a solid phase material with a digital microfluidic array enables a wide range of applications including solid phase extraction and sample concentration.
摘要翻译: 提供了用于在数字微流体装置上执行基于液滴的固相处理步骤的装置和方法。 可以形成或位于数字微流体元件上的固相材料,其可以是多孔固相材料,例如多孔聚合物整料。 固相可以通过原位方法形成,其中数字微流体阵列被致动以将液相的固相前体溶液输送到阵列上的所选元素,并且随后被处理以在阵列上形成固相 元件。 固相材料与数字微流体阵列的集成使得能够广泛应用于固相萃取和样品浓缩。
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