公开(公告)号：US20060189921A1

公开(公告)日：2006-08-24

申请号：US11406853

申请日：2006-04-19

申请人： Jason Galdonik ,  Matthew Ogle ,  James Pokorney

发明人： Jason Galdonik ,  Matthew Ogle ,  James Pokorney

IPC分类号： A61M1/00

CPC分类号： A61B17/22 ,  A61B2017/22034 ,  A61B2017/22035 ,  A61B2017/22079 ,  A61B2217/005 ,  A61F2/01

摘要： Methods for the removal of an embolism protection device use aspiration during the drawing of the embolism protection device into the catheter. Generally, the embolism protection device comprises a three dimensional filtering matrix that provides improved filtering without blocking the flow through the patient's vessel. In some embodiments, the embolism protection device can be actuated between a deployed configuration and a removal configuration with a reduced area across the cross section of the vessel lumen. The embolism protection device in the removal configuration can be drawn within the aspiration catheter. The aspiration catheter can have a distal portion with an expanded compartment with an average diameter at least about 20 percent larger than the average diameter of the shaft of the catheter within about 10 centimeters of the expanded compartment. In a rapid exchange version, the rapid exchange segment can have a length of at least about 10 centimeters.

摘要翻译： 在将栓塞保护装置拉入导管期间，用于去除栓塞保护装置的方法使用抽吸。 通常，栓塞保护装置包括三维过滤矩阵，其提供改进的过滤而不阻塞通过患者血管的流动。 在一些实施例中，栓塞保护装置可以在展开构造和移除构造之间被致动，并且在血管内腔的横截面上具有减小的面积。 拔除结构中的栓塞保护装置可以在抽吸导管内拉出。 抽吸导管可以具有远端部分，其具有扩张隔室，平均直径比扩张隔室的约10厘米内的导管轴的平均直径至少大约20％。 在快速交换版本中，快速交换段可以具有至少约10厘米的长度。

公开(公告)号：US20060200047A1

公开(公告)日：2006-09-07

申请号：US11072001

申请日：2005-03-04

申请人： Jason Galdonik ,  Matthew Ogle ,  James Pokorney ,  Kavitha Ganesan ,  Grace Wlodarski

发明人： Jason Galdonik ,  Matthew Ogle ,  James Pokorney ,  Kavitha Ganesan ,  Grace Wlodarski

IPC分类号： A61M29/00 ,  A61M25/00

CPC分类号： A61M25/0138 ,  A61M25/0054 ,  A61M25/0133

摘要： An integrated guiding device has a tube and a corewire within the tube and a torque coupler. The torque coupler can couple the rotational motion of the tube with the rotational motion of the corewire. The wire can be moved longitudinally at least some amount relative to the tube. The device can further comprise a functional medical structure, such as an embolism protection structure. The device can be used in medical procedures, such as less invasive procedures within the cardiovascular system. Improved fiber based embolism protection devices comprise fiber bundles that are twisted prior to delivery.

摘要翻译： 集成引导装置在管内具有管和芯线，以及扭矩耦合器。 扭矩耦合器可将管的旋转运动与芯线的旋转运动耦合。 电线可以相对于管子至少一定数量的纵向移动。 该装置还可以包括诸如栓塞保护结构的功能医疗结构。 该装置可用于医疗程序，例如心血管系统内的侵入性较小的程序。 改进的基于纤维的栓塞保护装置包括在输送之前被扭曲的纤维束。

公开(公告)号：US20050277976A1

公开(公告)日：2005-12-15

申请号：US10854920

申请日：2004-05-27

申请人： Jason Galdonik ,  Matthew Ogle ,  James Pokorney

发明人： Jason Galdonik ,  Matthew Ogle ,  James Pokorney

IPC分类号： A61B17/22 ,  A61F2/01 ,  A61M1/00 ,  A61M29/00

CPC分类号： A61B17/22 ,  A61B2017/22034 ,  A61B2017/22035 ,  A61B2017/22079 ,  A61B2217/005 ,  A61F2/01

摘要： Methods for the removal of an embolism protection device use aspiration during the drawing of the embolism protection device into the catheter. Generally, the embolism protection device comprises a three dimensional filtering matrix that provides improved filtering without blocking the flow through the patient's vessel. In some embodiments, the embolism protection device can be actuated between a deployed configuration and a removal configuration with a reduced area across the cross section of the vessel lumen. The embolism protection device in the removal configuration can be drawn within the aspiration catheter. The aspiration catheter can have a distal portion with an expanded compartment with an average diameter at least about 20 percent larger than the average diameter of the shaft of the catheter within about 10 centimeters of the expanded compartment. In a rapid exchange version, the rapid exchange segment can have a length of at least about 10 centimeters.

摘要翻译： 在将栓塞保护装置拉入导管期间，用于去除栓塞保护装置的方法使用抽吸。 通常，栓塞保护装置包括三维过滤矩阵，其提供改进的过滤而不阻塞通过患者血管的流动。 在一些实施例中，栓塞保护装置可以在展开构造和移除构造之间被致动，并且在血管内腔的横截面上具有减小的面积。 拔除结构中的栓塞保护装置可以在抽吸导管内拉出。 抽吸导管可以具有远端部分，其具有扩张隔室，平均直径比扩张隔室的约10厘米内的导管轴的平均直径至少大约20％。 在快速交换版本中，快速交换段可以具有至少约10厘米的长度。

公开(公告)号：US20060006649A1

公开(公告)日：2006-01-12

申请号：US11157476

申请日：2005-06-21

申请人： Jason Galdonik ,  James Pokorney ,  Matthew Ogle

发明人： Jason Galdonik ,  James Pokorney ,  Matthew Ogle

IPC分类号： F16L21/00

CPC分类号： A61M25/0905 ,  A61B2017/00477

摘要： A biocompatible medical device having a segmented element including a first segment having a first shaped interface and a second segment having a second shaped interface configured to operably couple the first shaped interface. When the first shaped interface is engaging the second shaped interface to form a joined segmented element, the first segment and the second segment cannot be decoupled by movement along an axis through the element. The medical device further includes a locking element configured to engage the joined segmented element with a sliding motion to prevent decoupling of the first segment with respect to the second segment by preventing significant relative movement of the segments with a component of the movement perpendicular to the axis.

摘要翻译： 一种具有分段元件的生物相容性医疗装置，其包括具有第一形状界面的第一区段和具有构造成可操作地连接第一成形界面的第二形状界面的第二区段。 当第一形状界面接合第二形状界面以形成连接的分段元件时，第一段和第二段不能通过沿着穿过该元件的轴的移动来解耦。 该医疗装置还包括锁定元件，该锁定元件构造成以滑动运动与接合的分段元件接合，以防止第一段相对于第二段解耦，这是通过阻止具有垂直于该轴线的运动分量的段的显着相对运动 。

公开(公告)号：US20050209631A1

公开(公告)日：2005-09-22

申请号：US10979439

申请日：2004-11-02

申请人： Jason Galdonik ,  James Pokorney ,  Matthew Ogle

发明人： Jason Galdonik ,  James Pokorney ,  Matthew Ogle

IPC分类号： A61M25/00 ,  A61M25/09 ,  A61M29/00

CPC分类号： A61M25/09016 ,  A61M25/0023 ,  A61M25/09025

摘要： An integrated guiding device has a tube and a corewire within the tube and a torque coupler. The torque coupler can couple the rotational motion of the tube with the rotational motion of the corewire. The wire can be moved longitudinally at least some amount relative to the tube. The device can further comprise a functional medical structure, such as an embolism protection structure. The device can be used in medical procedures, such as less invasive procedures within the cardiovascular system. Improved fiber based embolism protection devices comprise fiber bundles that are twisted prior to delivery.

摘要翻译： 集成引导装置在管内具有管和芯线，以及扭矩耦合器。 扭矩耦合器可将管的旋转运动与芯线的旋转运动耦合。 电线可以相对于管子至少一定数量的纵向移动。 该装置还可以包括诸如栓塞保护结构的功能医疗结构。 该装置可用于医疗程序，例如心血管系统内的侵入性较小的程序。 改进的基于纤维的栓塞保护装置包括在输送之前被扭曲的纤维束。

公开(公告)号：US20060247570A1

公开(公告)日：2006-11-02

申请号：US11335398

申请日：2006-01-18

申请人： James Pokorney

发明人： James Pokorney

IPC分类号： A61F2/24

CPC分类号： A61F2/24 ,  A61B17/3207 ,  A61B17/3421 ,  A61B2017/00243 ,  A61B2017/22014 ,  A61B2017/22097 ,  A61B2017/22098 ,  A61F2250/0059

摘要： This invention describes apical access methods and devices that enable repair, modification, removal, and/or replacement of a defective heart valve while allowing the beating heart to deliver blood flow through the defective valve annulus for an extended period of time in volumes sufficient to sustain life. The invention is comprised of a flow housing having a blood inflow opening, a blood outflow opening, and a one-way valve disposed within the flow housing between the inflow and outflow openings.

摘要翻译： 本发明描述了能够修复，修改，移除和/或更换有缺陷的心脏瓣膜的顶端进入方法和装置，同时允许跳动的心脏将血液流过有缺陷的瓣膜环，延长的时间段足以维持 生活。 本发明包括具有血液流入开口，血液流出开口和设置在流动壳体内的流入和流出开口之间的单向阀的流动壳体。

公开(公告)号：US20080091223A1

公开(公告)日：2008-04-17

申请号：US11974490

申请日：2007-10-12

申请人： James Pokorney ,  Stephanos Finitsis ,  John Kucharczyk

发明人： James Pokorney ,  Stephanos Finitsis ,  John Kucharczyk

IPC分类号： A61B17/22

CPC分类号： A61B17/221 ,  A61B2017/22034

摘要： A device capable of capturing and facilitating the removal of a thrombus in blood vessels (or stones in biliary or urinary ducts, or foreign bodies) uses a soft coil mesh with the aid of a pull wire or string to engage the surface of a thrombus, and remove the captured thrombus. The soft coil mesh is formed by an elongated microcoil element that forms the helical elements of a macrocoil element. The microcoil element provides a relatively elastic effect to the helical elements forming the macrocoil and allows for control of gripping forces on the thrombus while reducing non-rigid contact of the device with arterial walls. The use of multiple coil mesh elements, delivered through a single lumen or multiple lumens, preferably with separate control of at least one end of each coil, provides a firm grasp on a distal side of a thrombus, assisting in non-disruptive or minimally disrupted removal of the thrombus upon withdrawal of the device.

摘要翻译： 能够捕获和促进血管（或胆管或泌尿道或异物中的石块）的去除的装置使用软线圈网，借助于拉丝或绳子来接合血栓的表面， 并取出捕获的血栓。 软线圈网由形成大量线圈元件的螺旋元件的细长的微线圈元件形成。 微线圈元件对形成大螺线管的螺旋元件提供相对弹性的效果，并且允许控制血栓上的夹持力，同时减少装置与动脉壁的非刚性接触。 使用通过单个腔或多个流明递送的多个线圈网状元件，优选地具有每个线圈的至少一个端部的单独控制，在血栓的远端侧提供牢固的抓握，辅助非破坏性或最小程度的破坏 取出装置时取出血栓。

公开(公告)号：US20080009889A1

公开(公告)日：2008-01-10

申请号：US11825186

申请日：2007-07-05

申请人： James Pokorney ,  Kemal Schankereli

发明人： James Pokorney ,  Kemal Schankereli

IPC分类号： A61M39/00

CPC分类号： A61M39/0208

摘要： The primary object of the present invention is to provide an improved anastomotic connection between a conduit and a vessel by use of a cuff attached to one end of the conduit. By using a cuff, the conduit can be connected to a vessel without first cutting the vessel and without clamping the underlying vessel. In one embodiment of the invention, the cuff is contoured in the shape of a saddle to provide a connection cuff that contours to the cylindrical shape of the underlying vessel. The invention provides methods to connect the conduit to vessel without having the sutures located at the intersection of conduit and vessel, thereby minimizing the possibility that a secondary cutting operation of the vessel will also cutting the sutures. In one embodiment of the invention, a transition in compliance between the generally stiffer conduit and the generally softer vessel is accomplished by forming a compliance transitioning interface at the junction of the conduit and cuff.

摘要翻译： 本发明的主要目的是通过使用附接到导管的一端的袖带来提供导管和容器之间改进的吻合连接。 通过使用袖带，导管可以连接到容器而不首先切割容器而不夹紧下面的容器。 在本发明的一个实施例中，袖带的轮廓形状为鞍座，以提供与下面的容器的圆柱形形状轮廓的连接箍。 本发明提供了将导管连接到血管而不使缝合线位于导管和血管的交叉点处的方法，从而最小化血管的二次切割操作也将切断缝合线的可能性。 在本发明的一个实施例中，在通常更硬的导管和通常较软的容器之间的顺应性转变通过在导管和袖带的连接处形成柔顺过渡界面来实现。

公开(公告)号：US08409237B2

公开(公告)日：2013-04-02

申请号：US10854920

申请日：2004-05-27

申请人： Jason A. Galdonik ,  Matthew F. Ogle ,  James Pokorney

发明人： Jason A. Galdonik ,  Matthew F. Ogle ,  James Pokorney

IPC分类号： A61M29/00

CPC分类号： A61B17/22 ,  A61B2017/22034 ,  A61B2017/22035 ,  A61B2017/22079 ,  A61B2217/005 ,  A61F2/01

摘要： Methods for the removal of an embolism protection device use aspiration during the drawing of the embolism protection device into the catheter. Generally, the embolism protection device comprises a three dimensional filtering matrix that provides improved filtering without blocking the flow through the patient's vessel. In some embodiments, the embolism protection device can be actuated between a deployed configuration and a removal configuration with a reduced area across the cross section of the vessel lumen. The embolism protection device in the removal configuration can be drawn within the aspiration catheter. The aspiration catheter can have a distal portion with an expanded compartment with an average diameter at least about 20 percent larger than the average diameter of the shaft of the catheter within about 10 centimeters of the expanded compartment. In a rapid exchange version, the rapid exchange segment can have a length of at least about 10 centimeters.

摘要翻译： 在将栓塞保护装置拉入导管期间，用于去除栓塞保护装置的方法使用抽吸。 通常，栓塞保护装置包括三维过滤矩阵，其提供改进的过滤而不阻塞通过患者血管的流动。 在一些实施例中，栓塞保护装置可以在展开构造和移除构造之间被致动，并且在血管内腔的横截面上具有减小的面积。 拔除结构中的栓塞保护装置可以在抽吸导管内拉出。 抽吸导管可以具有远端部分，其具有扩张隔室，平均直径比扩张隔室的约10厘米内的导管轴的平均直径至少大约20％。 在快速交换版本中，快速交换段可以具有至少约10厘米的长度。

公开(公告)号：US08092483B2

公开(公告)日：2012-01-10

申请号：US11072001

申请日：2005-03-04

申请人： Jason A. Galdonik ,  Matthew F. Ogle ,  James Pokorney ,  Kavitha Ganesan ,  Grace Wlodarski

发明人： Jason A. Galdonik ,  Matthew F. Ogle ,  James Pokorney ,  Kavitha Ganesan ,  Grace Wlodarski

IPC分类号： A61M29/00

CPC分类号： A61M25/0138 ,  A61M25/0054 ,  A61M25/0133

摘要： An integrated guiding device has a tube and a corewire within the tube and a torque coupler. The torque coupler can couple the rotational motion of the tube with the rotational motion of the corewire. The wire can be moved longitudinally at least some amount relative to the tube. The device can further comprise a functional medical structure, such as an embolism protection structure. The device can be used in medical procedures, such as less invasive procedures within the cardiovascular system. Improved fiber based embolism protection devices comprise fiber bundles that are twisted prior to delivery.

摘要翻译： 集成引导装置在管内具有管和芯线，以及扭矩耦合器。 扭矩耦合器可将管的旋转运动与芯线的旋转运动耦合。 电线可以相对于管子至少一定数量的纵向移动。 该装置还可以包括诸如栓塞保护结构的功能医疗结构。 该装置可用于医疗程序，例如心血管系统内的侵入性较小的程序。 改进的基于纤维的栓塞保护装置包括在输送之前被扭曲的纤维束。