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    APPARATUS AND METHOD FOR ENDOTHELIAL KERATOPLASTY DONOR TISSUE TRANSPORT AND DELIVERY
    1.
    发明申请
    APPARATUS AND METHOD FOR ENDOTHELIAL KERATOPLASTY DONOR TISSUE TRANSPORT AND DELIVERY 审中-公开
    用于内皮激素组织运输和输送的装置和方法

    公开(公告)号：US20080281341A1

    公开(公告)日：2008-11-13

    申请号：US12119456

    申请日：2008-05-12

    申请人： Jason Miller ,  Jeffrey W. Speakman ,  Ahmed Al-Ghoul ,  Deepinder Dhaliwal

    发明人： Jason Miller ,  Jeffrey W. Speakman ,  Ahmed Al-Ghoul ,  Deepinder Dhaliwal

    IPC分类号： A61F9/007

    CPC分类号： A61F2/14 ,  A61F2/142 ,  A61F9/007

    摘要： A method for endothelial keratoplasty donor tissue transport and delivery to a recipient's eye, such as in DLEK, DSEK and DSAEK procedures, comprises the steps of: attaching endothelial keratoplasty donor tissue to a tissue holder, wherein the attachment between the tissue holder and the donor tissue is not on the endothelial layer of the endothelial keratoplasty donor tissue; placing the tissue holder and the attached donor tissue within a surrounding insertion tip; transporting the insertion tip to a position adjacent an access opening in the recipient's eye; inserting the tissue holder with the attached donor tissue through the opening and extending the tissue holder from within the insertion tip to position the donor tissue within the recipient's eye; and separating the attached donor tissue from the tissue holder with the tissue holder within the recipient's eye. An associated apparatus is disclosed.

    摘要翻译： 用于内皮角膜移植术供体组织输送和递送至接受者眼睛的方法，例如DLEK，DSEK和DSAEK方法，包括以下步骤：将内皮角膜移植术供体组织附着到组织支架上，其中组织支架和供体 组织不在内皮角膜移植术供体组织的内皮层上; 将组织保持器和附着的供体组织放置在周围的插入尖端内; 将插入尖端运送到接收者眼睛中与进入口相邻的位置; 通过所述开口插入具有附着的供体组织的组织保持器，并且将所述组织保持器从所述插入尖端内延伸以将所述供体组织定位在所述接收者的眼睛内; 以及将所述附着的供体组织与所述组织支架分离，以使所述组织保持器在所述受体的眼睛内。 公开了一种相关装置。

    Surface Treated Polymeric Synthetic Hernia Mesh Prosthesis, Surface Treated Sutures and Staples and Methods of Manufacturing the Same
    4.
    发明申请
    Surface Treated Polymeric Synthetic Hernia Mesh Prosthesis, Surface Treated Sutures and Staples and Methods of Manufacturing the Same 审中-公开
    表面处理聚合物合成疝网假体，表面处理缝线和钉子及其制造方法

    公开(公告)号：US20130110137A1

    公开(公告)日：2013-05-02

    申请号：US13632197

    申请日：2012-10-01

    申请人： Enrico Nicolo ,  Linda Cahalan ,  Greg Johnson ,  Mark Gartner ,  Patrick Cahalan ,  Brian J Fill ,  Ali HUSSAIN ,  Jeffrey W. Speakman

    发明人： Enrico Nicolo ,  Linda Cahalan ,  Greg Johnson ,  Mark Gartner ,  Patrick Cahalan ,  Brian J Fill ,  Ali HUSSAIN ,  Jeffrey W. Speakman

    IPC分类号： A61L27/24 ,  A61L27/22

    CPC分类号： A61L27/24 ,  A61L27/227 ,  A61L31/048 ,  A61L31/10 ,  A61L33/0029 ,  A61L2400/18 ,  A61M1/1698 ,  C08L83/04 ,  C08L23/12

    摘要： A variety of polymeric synthetic hernia mesh prosthesis with surface treatment on at least one tissue-facing surface to control tissue adhesion are disclosed including heparin surface treatment which provides heparin present in an amount to yield heparin bioactivity of at least one of i) an ATIII binding of at least 2 pmol/cm2, and ii) a thrombin deactivation of at least 0.2 IU/cm2; an acrylic surface treatment for coupling thereto of a heparin surface treatment, a collagen surface treatment or both; and an amino-functional polysiloxane surface treatment for coupling thereto of a heparin surface treatment. The synthetic hernia mesh may be formed of monofilament or multifilament polypropylene or polyester, and may be formed as a multi-layer prosthesis with an outer layer formed of a polymeric synthetic hernia mesh with surface treatment to control tissue adhesion coupled to one or more polymeric synthetic hernia meshes without such surface treatments.

    摘要翻译： 公开了在至少一个面向组织的表面上进行表面处理以控制组织粘附的各种聚合合成疝网假体，其包括肝素表面处理，其提供一定量的肝素以产生以下至少一种的肝素生物活性：i）ATIII结合 至少2pmol / cm 2，和ii）至少0.2IU / cm 2的凝血酶失活; 用于与肝素表面处理，胶原表面处理或两者结合的丙烯酸表面处理; 和用于与肝素表面处理偶联的氨基官能聚硅氧烷表面处理。 合成疝网可以由单丝或多丝聚丙烯或聚酯形成，并且可以形成为具有由聚合物合成疝网形成的外层的多层假体，其具有表面处理以控制与一种或多种聚合物合成 没有这种表面处理的疝气网眼。