公开(公告)号：US5154912A

公开(公告)日：1992-10-13

申请号：US587176

申请日：1990-09-20

Applicant: Jean-Pierre Schirmann ,  Jean-Jacques Barieux

Inventor： Jean-Pierre Schirmann ,  Jean-Jacques Barieux

IPC: C01B15/01 ,  C01B15/023 ,  C07B59/00 ,  C07C67/00 ,  C07C407/00 ,  C07C409/00 ,  C07C409/16 ,  C07C409/18 ,  C07C409/40 ,  C07C409/42

CPC classification number: C01B15/01 ,  C07C409/18 ,  C07C409/20 ,  C07C409/24 ,  C07C409/30 ,  C07C409/32 ,  C07C409/38 ,  C07C409/42 ,  C07B2200/05 ,  C07C2101/14

Abstract: The peroxides which include the O.sup.17 isotope, especially the hydrogen peroxides and peroxides and hydroperoxides prepared therefrom, are well adapted as nonradioactive labeled compounds for use in the medicinal and biological arts.

Abstract translation: 包括O17同位素，特别是过氧化氢和由此制备的过氧化氢和氢过氧化物的过氧化物，很好地适用于药物和生物学领域中的非放射性标记化合物。

公开(公告)号：US4238612A

公开(公告)日：1980-12-09

申请号：US22544

申请日：1979-03-21

Applicant: Jean-Jacques Barieux ,  Marie-Christine Dubroeucq ,  Francois Rocquet

Inventor： Jean-Jacques Barieux ,  Marie-Christine Dubroeucq ,  Francois Rocquet

IPC: C07D211/30 ,  C07D211/12 ,  C07D211/22 ,  C07D211/34 ,  C07D401/06 ,  C07D211/32

CPC classification number: C07D211/34 ,  C07D211/12 ,  C07D211/22

Abstract: A process for the conversion of compounds of the formula: ##STR1## in which R is a hydrogen atom or a substituent and for which the carbon carrying the vinyl group has the rectus configuration, into the corresponding compounds of formula (I) for which the carbon carrying the vinyl group has the sinister configuration, and vice versa, which comprises subjecting a compound of formula (I) for which the carbon carrying the vinyl group has the rectus or sinister configuration, partially or entirely salified, to a heating at a temperature above 50.degree. C. in a protic solvent or a mixture of protic solvents in the presence or absence of formaldehyde, and isolating the compound of formula (I) for which the carbon carrying the vinyl group has the sinister or rectus configuration thus formed.

Abstract translation: 将式（I）化合物转化成式（I）化合物的方法，其中R是氢原子或取代基并且带有乙烯基的碳具有直链构型， 其中携带乙烯基的碳具有阴性构型，反之亦然，其中包括使带有乙烯基的碳直接或阴性构型的部分或全部成盐的式（I）化合物加热 在质子溶剂或质子溶剂的混合物中，在存在或不存在甲醛的情况下，在高于50℃的温度下，分离出其中携带乙烯基的碳具有阴性或直肠构型的式（I）化合物，因此 形成。