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公开(公告)号:US20090054445A1
公开(公告)日:2009-02-26
申请号:US12162002
申请日:2007-01-25
申请人: Jeffrey Albert , Cristobal Alhambra , James Kang , Gerard Koether , Yan Li , Thomas Simpson , James Woods
发明人: Jeffrey Albert , Cristobal Alhambra , James Kang , Gerard Koether , Yan Li , Thomas Simpson , James Woods
IPC分类号: A61K31/4709 , C07D215/20 , A61K31/501 , A61P25/00 , C07D403/12
CPC分类号: C07D405/12 , C07D401/12 , C07D409/12 , C07D413/12 , C07D417/12
摘要: Compounds of Formula I wherein R1, A, R2, n, R3, m, R4, R5 and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
摘要翻译: 式I化合物,其中R 1,A,R 2,n,R 3,m,R 4,R 5和q如本说明书中所述,药学上可接受的盐,制备方法,药物组合物及其使用方法。
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公开(公告)号:US20100029717A1
公开(公告)日:2010-02-04
申请号:US12576319
申请日:2009-10-09
申请人: Thomas Simpson , James Kang , Jeffrey Albert , Cristobal Alhambra , Gerard Koether , James Woods , Yan Li
发明人: Thomas Simpson , James Kang , Jeffrey Albert , Cristobal Alhambra , Gerard Koether , James Woods , Yan Li
CPC分类号: C07D215/38 , C07D215/14 , C07D215/52
摘要: Compounds of Formula I wherein R1, A, R2, R3, R4, R5, R8, n, m, q and r are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
摘要翻译: 其中R 1,A,R 2,R 3,R 4,R 5,R 8,n,m,q和r如说明书中所述的式I化合物,药学上可接受的盐,制备方法,含药物组合物和使用方法 相同。
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公开(公告)号:US20080293765A1
公开(公告)日:2008-11-27
申请号:US12096997
申请日:2006-12-11
申请人: Jeffrey Albert , Cristobal Alhambra , James Kang , Gerard Koether , Thomas Simpson , James Woods , Yan Li
发明人: Jeffrey Albert , Cristobal Alhambra , James Kang , Gerard Koether , Thomas Simpson , James Woods , Yan Li
IPC分类号: A61K31/47 , A61P25/00 , A61P3/04 , A61P29/00 , A61P11/00 , A61P35/00 , C07D215/38 , C07D215/48
CPC分类号: C07D215/38 , C07D215/14 , C07D215/52
摘要: Compounds of Formula I wherein R1, A, R2, R3, R4, R5, R8, n, m, q and r are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
摘要翻译: 其中R 1,A,R 2,R 3,R 4,R 5,R 8,n,m,q和r如说明书中所述的式I化合物,药学上可接受的盐,制备方法,含药物组合物和使用方法 相同。
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公开(公告)号:US20080021062A1
公开(公告)日:2008-01-24
申请号:US11609166
申请日:2006-12-11
申请人: Thomas Simpson , James Kang , Jeffrey Albert , Cristobal Alhambra , Gerard Koether , James Woods , Yan Li
发明人: Thomas Simpson , James Kang , Jeffrey Albert , Cristobal Alhambra , Gerard Koether , James Woods , Yan Li
CPC分类号: C07D215/38 , C07D215/14 , C07D215/52
摘要: Compounds of Formula II wherein R1, A, R2, R3, R4, R5, R8, n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
摘要翻译: 式II的化合物,其中R 1,A,R 2,R 3,R 4,R 4, R 5,R 8,n,m和q如说明书中所述,药学上可接受的盐,制备方法,药物组合物及其使用方法。
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公开(公告)号:US08071621B2
公开(公告)日:2011-12-06
申请号:US12576319
申请日:2009-10-09
申请人: Thomas Simpson , James Kang , Jeffrey Albert , Cristobal Alhambra , Gerard Koether , James Woods , Yan Li
发明人: Thomas Simpson , James Kang , Jeffrey Albert , Cristobal Alhambra , Gerard Koether , James Woods , Yan Li
CPC分类号: C07D215/38 , C07D215/14 , C07D215/52
摘要: Compounds of Formula I wherein R1, A, R2, R3, R4, R5, R8, n, m, q and r are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
摘要翻译: 其中R 1,A,R 2,R 3,R 4,R 5,R 8,n,m,q和r如说明书中所述的式I化合物,药学上可接受的盐,制备方法,含药物组合物和使用方法 相同。
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公开(公告)号:US20080200500A1
公开(公告)日:2008-08-21
申请号:US11914583
申请日:2006-05-30
申请人: Thomas R. Simpson , James Kang , S. Jeffrey Albert , Cristobal Alhambra , M. Gerard Koether , M. James Woods , Yan Li
发明人: Thomas R. Simpson , James Kang , S. Jeffrey Albert , Cristobal Alhambra , M. Gerard Koether , M. James Woods , Yan Li
IPC分类号: A61K31/472 , C07D215/52 , A61P25/18 , A61P3/04 , A61P25/24 , A61P25/22
CPC分类号: C07D215/52
摘要: Compounds of Formula I wherein R1, A, R2, n, R3, m, R5 and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
摘要翻译: 式I的化合物,其中R 1,A,R 2,n,R 3,m,R 5, 和q如说明书中所述,药学上可接受的盐,制备方法,含药物组合物及其使用方法。
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公开(公告)号:US20080306110A1
公开(公告)日:2008-12-11
申请号:US12067566
申请日:2006-09-19
申请人: Jeffrey S. Albert , Cristobal Alhambra , James Kang , Gerard M. Koether , Thomas R. Simpson , James Woods , Yan Li
发明人: Jeffrey S. Albert , Cristobal Alhambra , James Kang , Gerard M. Koether , Thomas R. Simpson , James Woods , Yan Li
IPC分类号: A61K31/47 , A61P25/00 , A61P29/00 , A61P11/00 , C07D215/48
CPC分类号: C07D215/52
摘要: Compounds of Formula I wherein R1, A, R2, R3, R4, R5, n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
摘要翻译: 其中R 1,A,R 2,R 3,R 4,R 5,n,m和q如说明书中所述的式I化合物,药学上可接受的盐,制备方法,药物组合物及其使用方法。
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公开(公告)号:US20080280949A1
公开(公告)日:2008-11-13
申请号:US12063136
申请日:2006-08-10
申请人: Jeffrey S. Albert , Cristobal Alhambra , James Kang , Gerard M. Koether , Thomas R. Simpson , James Woods , Yan Li
发明人: Jeffrey S. Albert , Cristobal Alhambra , James Kang , Gerard M. Koether , Thomas R. Simpson , James Woods , Yan Li
IPC分类号: C07D401/12 , A61K31/4709 , A61P11/00 , A61P25/00 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P29/00 , A61P35/00
CPC分类号: C07D401/12
摘要: Compounds of Formula I wherein R1, A, R2, R3, R4, R5, n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
摘要翻译: 式Ⅰ的化合物,其中R 1,A,R 2,R 3,R 4,R 4, 其中n,m和q如说明书中所述,药学上可接受的盐,制备方法,药物组合物及其使用方法。
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公开(公告)号:US20080214605A1
公开(公告)日:2008-09-04
申请号:US12067572
申请日:2006-09-19
申请人: Jeffrey S. Albert , Gerard M. Koether , Cristobal Alhambra , James Kang , Thomas R. Simpson , James Woods , Yan Li
发明人: Jeffrey S. Albert , Gerard M. Koether , Cristobal Alhambra , James Kang , Thomas R. Simpson , James Woods , Yan Li
IPC分类号: A61K31/472 , C07D215/00 , C07D215/38 , A61P25/00 , A61P3/00 , A61P1/00 , A61P15/00 , A61P35/04
CPC分类号: C07D215/52 , C07D401/12
摘要: Compounds of Formula I wherein R1, A, R2, R3, R4, R5, n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
摘要翻译: 式Ⅰ的化合物,其中R 1,A,R 2,R 3,R 4,R 4, 其中n,m和q如说明书中所述,药学上可接受的盐,制备方法,药物组合物及其使用方法。
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公开(公告)号:US20080194622A1
公开(公告)日:2008-08-14
申请号:US11917820
申请日:2006-06-21
申请人: Thomas R. Simpson , James Kang , Jeffrey S. Albert , Cristobal Alhambra , Gerard M. Koether , James Woods , Yan Li
发明人: Thomas R. Simpson , James Kang , Jeffrey S. Albert , Cristobal Alhambra , Gerard M. Koether , James Woods , Yan Li
CPC分类号: C07D215/52
摘要: Compounds of Formula I wherein R1, A, R2, R3, R4, R5 n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
摘要翻译: 式Ⅰ的化合物,其中R 1,A,R 2,R 3,R 4,R 4, m和q如说明书,药学上可接受的盐,制备方法,药物组合物含有及其使用方法所述。
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