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公开(公告)号:US09127268B2
公开(公告)日:2015-09-08
申请号:US13514952
申请日:2010-12-10
申请人: Jeffry Dean Watkins , Alain Philippe Vasserot , Leslie Ann Greene , Ryan Andrew Adams , Kristi Helen Piehl , Fei Hong , Kyle P. Chiang , Wei Zhang , Alina He
发明人: Jeffry Dean Watkins , Alain Philippe Vasserot , Leslie Ann Greene , Ryan Andrew Adams , Kristi Helen Piehl , Fei Hong , Kyle P. Chiang , Wei Zhang , Alina He
IPC分类号: C12N9/00 , A61K38/53 , A61K39/395 , A61K45/06
CPC分类号: A61K38/53 , A61K39/39541 , A61K45/06 , C12N9/93 , C12Y601/01021
摘要: Inflammatory and other cellular response-modulating compositions are provided comprising aminoacyl-tRNA synthetase polypeptides, including active fragments and/or variants thereof. Also provided are methods of using such compositions in the treatment of conditions that benefit from the modulation of inflammation, such as inflammatory diseases or conditions.
摘要翻译: 提供包含氨基-tRNA合成酶多肽的炎症和其它细胞应答调节组合物,包括其活性片段和/或变体。 还提供了使用这些组合物来治疗受益于炎症疾病或病症等炎症调节的病症的方法。
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公开(公告)号:US20130108630A1
公开(公告)日:2013-05-02
申请号:US13514952
申请日:2010-12-10
申请人: Jeffry Dean Watkins , Alain Philippe Vasserot , Leslie Ann Greene , Ryan Andrew Adams , Kyle P. Chiang , Wei Zhang , Kristi Helen Piehl , Fei Hong , Alina He
发明人: Jeffry Dean Watkins , Alain Philippe Vasserot , Leslie Ann Greene , Ryan Andrew Adams , Kyle P. Chiang , Wei Zhang , Kristi Helen Piehl , Fei Hong , Alina He
IPC分类号: A61K38/53 , A61K45/06 , A61K39/395
CPC分类号: A61K38/53 , A61K39/39541 , A61K45/06 , C12N9/93 , C12Y601/01021
摘要: Inflammatory and other cellular response-modulating compositions are provided comprising aminoacyl-tRNA synthetase polypeptides, including active fragments and/or variants thereof. Also provided are methods of using such compositions in the treatment of conditions that benefit from the modulation of inflammation, such as inflammatory diseases or conditions.
摘要翻译: 提供包含氨基-tRNA合成酶多肽的炎症和其它细胞应答调节组合物,包括其活性片段和/或变体。 还提供了使用这些组合物来治疗受益于炎症疾病或病症等炎症调节的病症的方法。
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