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1.
公开(公告)号:US6019985A
公开(公告)日:2000-02-01
申请号:US32141
申请日:1998-02-27
IPC分类号: A61K35/74 , A61K39/012 , A61K39/39 , A61P33/00 , A61P37/04 , A61K39/002 , A61K39/00 , A61K39/12 , A61K39/02 , A61K39/385
CPC分类号: A61K39/012 , A61K35/74 , A61K39/39 , Y10S424/816 , Y10S424/826
摘要: Methods are provided for improved immunization against coccidiosis and other bacterial, viral, or parasitic diseases in poultry. One method includes administering a solution of Propionibacterium acnes suspended in normal saline to a chick at age day one, following hatching. An anticoccidial vaccine and/or other vaccine is then administered to the chick such as by oral administration. Alternatively the method includes the steps of aseptically injecting Propionibacterium acnes in ovo at about day 18 in development, followed by post-hatching vaccination with an anticoccidial vaccine and/or other vaccine. Alternatively, either method can be utilized without the subsequent vaccination step for stimulating non-specific cell-mediated immune responses in poultry.
摘要翻译: 提供了用于改善家禽抗球虫病和其他细菌,病毒或寄生虫病的免疫的方法。 一种方法包括在孵化后,在第一天将悬浮在生理盐水中的痤疮丙酸杆菌溶液施用于小鸡。 然后将抗球虫疫苗和/或其它疫苗例如通过口服施用给小鸡。 或者,该方法包括以下步骤:在大约第18天在开发中无菌地注射痤疮丙酸杆菌,随后用抗球虫疫苗和/或其他疫苗进行孵化后疫苗接种。 或者,可以利用任一方法,而不用随后的用于刺激家禽中非特异性细胞介导的免疫应答的接种步骤。