公开(公告)号：US20120100163A1

公开(公告)日：2012-04-26

申请号：US13274210

申请日：2011-10-14

Applicant: Jens BRIMNES ,  Kaare LUND

Inventor： Jens BRIMNES ,  Kaare LUND

IPC: A61K39/00 ,  A61P37/06

CPC classification number: A61K39/36 ,  A61K39/35 ,  A61K2039/542 ,  A61K2039/544 ,  A61K2039/545 ,  A61K2039/58

Abstract: The present invention relates to antigens and methods for the suppression of a hypersensitivity immune response via bystander suppression with an antigen unrelated to the allergen triggering a hypersensitivity immune response such as an allergic response in an individual. Treatment regiments covering the administering the unrelated antigen to the oral cavity (e.g. sublingual mucosa) combined with the administration of the unrelated antigen to either the respiratory tract, gastro-intestinal tract or skin in a simultaneous, contemporaneous, separate or sequential manner is provided.

Abstract translation: 本发明涉及抗原和通过旁观者抑制的过敏免疫应答的方法，所述抗原与过敏原无关的抗原触发了超敏反应免疫应答，例如个体的过敏反应。 提供了涉及向口腔（例如舌下粘膜）施用无关抗原与将不相关抗原以同时，同时期，分开或连续方式施用于呼吸道，胃肠道或皮肤的治疗团。