公开(公告)号：US07553675B2

公开(公告)日：2009-06-30

申请号：US11622201

申请日：2007-01-11

申请人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer ,  Paul Lambotte ,  Paul J. Lawrence

发明人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer ,  Paul Lambotte ,  Paul J. Lawrence

IPC分类号： G01N33/53

CPC分类号： G01N21/8483 ,  B01L3/5023 ,  G01N33/54386 ,  G01N33/558 ,  Y10S435/805 ,  Y10S435/823 ,  Y10S436/807 ,  Y10S436/81 ,  Y10S436/823 ,  Y10T436/25125

摘要： A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support or member bearing a mark thereon, and a matrix or member containing a capture zone. In operation, an observation area in the test device becomes transparent, thereby allowing the user to view a mark that is present on a support that is disposed beneath the observation area. Typically, the mark on the underlying support is configured as a minus (−) sign. In the absence of analyte in the sample, the test device presents a negative result as a minus (−) signal. In the presence of analyte in the sample, however, the mark operates in concert with a perpendicular test line on the observation area to present a positive result as a plus (+) signal that is visible to the user.

摘要翻译： 一种用于确定流体样品中一种或多种分析物的存在或不存在的测试装置和方法，所述测试装置包括在其上具有标记的支撑件或构件，以及包含捕获区的基质或构件。 在操作中，测试装置中的观察区域变得透明，从而允许用户观看存在于设置在观察区域下方的支撑体上的标记。 通常，底层支持上的标记被配置为减号（ - ）。 在样品中没有分析物的情况下，测试装置呈负值（-1）信号。 然而，在样品中存在分析物的情况下，标记与观察区域上的垂直测试线一致，以将正的结果呈现为使用者可见的加号（+）信号。

公开(公告)号：US06855561B2

公开(公告)日：2005-02-15

申请号：US09950366

申请日：2001-09-10

申请人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer

发明人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer

IPC分类号： G01N21/86 ,  G01N33/543 ,  G01N33/558 ,  G01N33/53

CPC分类号： G01N21/8483 ,  B01L3/5023 ,  G01N33/54386 ,  G01N33/558 ,  Y10S435/805 ,  Y10S435/823 ,  Y10S436/807 ,  Y10S436/81 ,  Y10S436/823 ,  Y10T436/25125

摘要： A test device and method for determining the presence or absence of an analyte in a fluid sample, the test device including a support bearing a mark thereon, and a matrix defining an axial flow path. In operation, an observation area in the test device becomes transparent, thereby allowing the user to view a mark that is present on a support that is disposed beneath the observation area. Typically, the mark on the underlying support is configured as a minus (−) sign. In the absence of analyte in the sample, the test device presents a negative result as a minus (−) signal. In the presence of analyte in the sample, however, the mark operates in concert with a perpendicular test line on the observation area to present a positive result as a plus (+) signal that is visible to the user.

摘要翻译： 一种用于确定流体样品中分析物的存在或不存在的测试装置和方法，所述测试装置包括在其上具有标记的支撑件和限定轴向流动路径的矩阵。 在操作中，测试装置中的观察区域变得透明，从而允许用户观看存在于设置在观察区域下方的支撑体上的标记。 通常，底层支持上的标记被配置为减号（ - ）。 在样品中没有分析物的情况下，测试装置呈负值（-1）信号。 然而，在样品中存在分析物的情况下，标记与观察区域上的垂直测试线一致，以将正的结果呈现为使用者可见的加号（+）信号。

公开(公告)号：US08030091B2

公开(公告)日：2011-10-04

申请号：US12423697

申请日：2009-04-14

申请人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer ,  Paul Lambotte ,  Paul J. Lawrence

发明人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer ,  Paul Lambotte ,  Paul J. Lawrence

IPC分类号： G01N33/543

CPC分类号： G01N21/8483 ,  B01L3/5023 ,  G01N33/54386 ,  G01N33/558 ,  Y10S435/805 ,  Y10S435/823 ,  Y10S436/807 ,  Y10S436/81 ,  Y10S436/823 ,  Y10T436/25125

摘要： A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support or member bearing a mark thereon, and a matrix or member containing a capture zone. In operation, an observation area in the test device becomes transparent, thereby allowing the user to view a mark that is present on a support that is disposed beneath the observation area. Typically, the mark on the underlying support is configured as a minus (−) sign. In the absence of analyte in the sample, the test device presents a negative result as a minus (−) signal. In the presence of analyte in the sample, however, the mark operates in concert with a perpendicular test line on the observation area to present a positive result as a plus (+) signal that is visible to the user.

摘要翻译： 一种用于确定流体样品中一种或多种分析物的存在或不存在的测试装置和方法，所述测试装置包括在其上具有标记的支撑件或构件，以及包含捕获区的基质或构件。 在操作中，测试装置中的观察区域变得透明，从而允许用户观看存在于设置在观察区域下方的支撑体上的标记。 通常，底层支持上的标记被配置为减号（ - ）。 在样品中没有分析物的情况下，测试装置呈负值（-1）信号。 然而，在样品中存在分析物的情况下，标记与观察区域上的垂直测试线一致，以将正的结果呈现为使用者可见的加号（+）信号。

公开(公告)号：US20070111323A1

公开(公告)日：2007-05-17

申请号：US11622201

申请日：2007-01-11

申请人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer ,  Paul Lambotte ,  Paul Lawrence

发明人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer ,  Paul Lambotte ,  Paul Lawrence

IPC分类号： G01N33/558

CPC分类号： G01N21/8483 ,  B01L3/5023 ,  G01N33/54386 ,  G01N33/558 ,  Y10S435/805 ,  Y10S435/823 ,  Y10S436/807 ,  Y10S436/81 ,  Y10S436/823 ,  Y10T436/25125

摘要： A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support or member bearing a mark thereon, and a matrix or member containing a capture zone. In operation, an observation area in the test device becomes transparent, thereby allowing the user to view a mark that is present on a support that is disposed beneath the observation area. Typically, the mark on the underlying support is configured as a minus (−) sign. In the absence of analyte in the sample, the test device presents a negative result as a minus (−) signal. In the presence of analyte in the sample, however, the mark operates in concert with a perpendicular test line on the observation area to present a positive result as a plus (+) signal that is visible to the user.

摘要翻译： 一种用于确定流体样品中一种或多种分析物的存在或不存在的测试装置和方法，所述测试装置包括在其上具有标记的支撑件或构件，以及包含捕获区的基质或构件。 在操作中，测试装置中的观察区域变得透明，从而允许用户观看存在于设置在观察区域下方的支撑体上的标记。 通常，底层支持上的标记被配置为减号（ - ）。 在样品中没有分析物的情况下，测试装置呈负值（-1）信号。 然而，在样品中存在分析物的情况下，标记与观察区域上的垂直测试线一致，以将正的结果呈现为使用者可见的加号（+）信号。

公开(公告)号：US07537937B2

公开(公告)日：2009-05-26

申请号：US11757270

申请日：2007-06-01

申请人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer

发明人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer

IPC分类号： G01N33/53

CPC分类号： G01N21/8483 ,  B01L3/5023 ,  G01N33/54386 ,  G01N33/558 ,  Y10S435/805 ,  Y10S435/823 ,  Y10S436/807 ,  Y10S436/81 ,  Y10S436/823 ,  Y10T436/25125

摘要： A test device and method for determining the presence or absence of an analyte in a fluid sample, the test device including a support bearing a mark thereon, and a matrix defining an axial flow path. In operation, an observation area in the test device becomes transparent, thereby allowing the user to view a mark that is present on a support that is disposed beneath the observation area. Typically, the mark on the underlying support is configured as a minus (−) sign. In the absence of analyte in the sample, the test device presents a negative result as a minus (−) signal. In the presence of analyte in the sample, however, the mark operates in concert with a perpendicular test line on the observation area to present a positive result as a plus (+) signal that is visible to the user.

摘要翻译： 一种用于确定流体样品中分析物的存在或不存在的测试装置和方法，所述测试装置包括在其上具有标记的支撑件和限定轴向流动路径的矩阵。 在操作中，测试装置中的观察区域变得透明，从而允许用户观看存在于设置在观察区域下方的支撑体上的标记。 通常，底层支持上的标记被配置为减号（ - ）。 在样品中没有分析物的情况下，测试装置呈负值（-1）信号。 然而，在样品中存在分析物的情况下，标记与观察区域上的垂直测试线一致，以将正的结果呈现为使用者可见的加号（+）信号。

公开(公告)号：US07226793B2

公开(公告)日：2007-06-05

申请号：US10461157

申请日：2003-06-12

申请人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer

发明人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer

IPC分类号： G01N33/53

CPC分类号： G01N21/8483 ,  B01L3/5023 ,  G01N33/54386 ,  G01N33/558 ,  Y10S435/805 ,  Y10S435/823 ,  Y10S436/807 ,  Y10S436/81 ,  Y10S436/823 ,  Y10T436/25125

摘要： A test device and method for determining the presence or absence of an analyte in a fluid sample, the test device including a support bearing a mark thereon, and a matrix defining an axial flow path. In operation, an observation area in the test device becomes transparent, thereby allowing the user to view a mark that is present on a support that is disposed beneath the observation area. Typically, the mark on the underlying support is configured as a minus (−) sign. In the absence of analyte in the sample, the test device presents a negative result as a minus (−) signal. In the presence of analyte in the sample, however, the mark operates in concert with a perpendicular test line on the observation area to present a positive result as a plus (+) signal that is visible to the user.

摘要翻译： 一种用于确定流体样品中分析物的存在或不存在的测试装置和方法，所述测试装置包括在其上具有标记的支撑件和限定轴向流动路径的矩阵。 在操作中，测试装置中的观察区域变得透明，从而允许用户观看存在于设置在观察区域下方的支撑体上的标记。 通常，底层支持上的标记被配置为减号（ - ）。 在样品中没有分析物的情况下，测试装置呈负值（-1）信号。 然而，在样品中存在分析物的情况下，标记与观察区域上的垂直测试线一致，以将正的结果呈现为使用者可见的加号（+）信号。

公开(公告)号：US07179657B2

公开(公告)日：2007-02-20

申请号：US10241822

申请日：2002-09-10

申请人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer ,  Paul Lambotte ,  Paul J. Lawrence

发明人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer ,  Paul Lambotte ,  Paul J. Lawrence

IPC分类号： G01N33/533

CPC分类号： G01N21/8483 ,  B01L3/5023 ,  G01N33/54386 ,  G01N33/558 ,  Y10S435/805 ,  Y10S435/823 ,  Y10S436/807 ,  Y10S436/81 ,  Y10S436/823 ,  Y10T436/25125

摘要： A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support or member bearing a mark thereon, and a matrix or member containing a capture zone. In operation, an observation area in the test device becomes transparent, thereby allowing the user to view a mark that is present on a support that is disposed beneath the observation area. Typically, the mark on the underlying support is configured as a minus (−) sign. In the absence of analyte in the sample, the test device presents a negative result as a minus (−) signal. In the presence of analyte in the sample, however, the mark operates in concert with a perpendicular test line on the observation area to present a positive result as a plus (+) signal that is visible to the user.

摘要翻译： 一种用于确定流体样品中一种或多种分析物的存在或不存在的测试装置和方法，所述测试装置包括在其上具有标记的支撑件或构件，以及包含捕获区的基质或构件。 在操作中，测试装置中的观察区域变得透明，从而允许用户观看存在于设置在观察区域下方的支撑体上的标记。 通常，底层支持上的标记被配置为减号（ - ）。 在样品中没有分析物的情况下，测试装置呈负值（-1）信号。 然而，在样品中存在分析物的情况下，标记与观察区域上的垂直测试线一致，以将正的结果呈现为使用者可见的加号（+）信号。

公开(公告)号：US08202734B2

公开(公告)日：2012-06-19

申请号：US12423729

申请日：2009-04-14

申请人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer

发明人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer

IPC分类号： G01N33/53

CPC分类号： G01N21/8483 ,  B01L3/5023 ,  G01N33/54386 ,  G01N33/558 ,  Y10S435/805 ,  Y10S435/823 ,  Y10S436/807 ,  Y10S436/81 ,  Y10S436/823 ,  Y10T436/25125

摘要： A test device and method for determining the presence or absence of an analyte in a fluid sample, the test device including a support bearing a mark thereon, and a matrix defining an axial flow path. In operation, an observation area in the test device becomes transparent, thereby allowing the user to view a mark that is present on a support that is disposed beneath the observation area. Typically, the mark on the underlying support is configured as a minus (−) sign. In the absence of analyte in the sample, the test device presents a negative result as a minus (−) signal. In the presence of analyte in the sample, however, the mark operates in concert with a perpendicular test line on the observation area to present a positive result as a plus (+) signal that is visible to the user.

摘要翻译： 一种用于确定流体样品中分析物的存在或不存在的测试装置和方法，所述测试装置包括在其上具有标记的支撑件和限定轴向流动路径的矩阵。 在操作中，测试装置中的观察区域变得透明，从而允许用户观看存在于设置在观察区域下方的支撑体上的标记。 通常，底层支持上的标记被配置为减号（ - ）。 在样品中没有分析物的情况下，测试装置呈负值（-1）信号。 然而，在样品中存在分析物的情况下，标记与观察区域上的垂直测试线一致，以将正的结果呈现为使用者可见的加号（+）信号。

公开(公告)号：US20120021528A1

公开(公告)日：2012-01-26

申请号：US13252100

申请日：2011-10-03

申请人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer ,  Paul Lambotte ,  Paul J. Lawrence

发明人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer ,  Paul Lambotte ,  Paul J. Lawrence

IPC分类号： G01N21/77

CPC分类号： G01N21/8483 ,  B01L3/5023 ,  G01N33/54386 ,  G01N33/558 ,  Y10S435/805 ,  Y10S435/823 ,  Y10S436/807 ,  Y10S436/81 ,  Y10S436/823 ,  Y10T436/25125

摘要： A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support or member bearing a mark thereon, and a matrix or member containing a capture zone. In operation, an observation area in the test device becomes transparent, thereby allowing the user to view a mark that is present on a support that is disposed beneath the observation area. Typically, the mark on the underlying support is configured as a minus (−) sign. In the absence of analyte in the sample, the test device presents a negative result as a minus (−) signal. In the presence of analyte in the sample, however, the mark operates in concert with a perpendicular test line on the observation area to present a positive result as a plus (+) signal that is visible to the user.

摘要翻译： 一种用于确定流体样品中一种或多种分析物的存在或不存在的测试装置和方法，所述测试装置包括在其上具有标记的支撑件或构件，以及包含捕获区的基质或构件。 在操作中，测试装置中的观察区域变得透明，从而允许用户观看存在于设置在观察区域下方的支撑体上的标记。 通常，底层支持上的标记被配置为减号（ - ）。 在样品中没有分析物的情况下，测试装置呈负值（-1）信号。 然而，在样品中存在分析物的情况下，标记与观察区域上的垂直测试线一致，以将正的结果呈现为使用者可见的加号（+）信号。

公开(公告)号：US20090221101A1

公开(公告)日：2009-09-03

申请号：US12423697

申请日：2009-04-14

申请人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer

发明人： Jeremy Jerome ,  Mark Daquipa ,  Bruce Jacono ,  Hans Boehringer

IPC分类号： G01N33/543 ,  G01N31/22

CPC分类号： G01N21/8483 ,  B01L3/5023 ,  G01N33/54386 ,  G01N33/558 ,  Y10S435/805 ,  Y10S435/823 ,  Y10S436/807 ,  Y10S436/81 ,  Y10S436/823 ,  Y10T436/25125

摘要： A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support or member bearing a mark thereon, and a matrix or member containing a capture zone. In operation, an observation area in the test device becomes transparent, thereby allowing the user to view a mark that is present on a support that is disposed beneath the observation area. Typically, the mark on the underlying support is configured as a minus (−) sign. In the absence of analyte in the sample, the test device presents a negative result as a minus (−) signal. In the presence of analyte in the sample, however, the mark operates in concert with a perpendicular test line on the observation area to present a positive result as a plus (+) signal that is visible to the user.

摘要翻译： 一种用于确定流体样品中一种或多种分析物的存在或不存在的测试装置和方法，所述测试装置包括在其上具有标记的支撑件或构件，以及包含捕获区的基质或构件。 在操作中，测试装置中的观察区域变得透明，从而允许用户观看存在于设置在观察区域下方的支撑体上的标记。 通常，底层支持上的标记被配置为减号（ - ）。 在样品中没有分析物的情况下，测试装置呈负值（-1）信号。 然而，在样品中存在分析物的情况下，标记与观察区域上的垂直测试线一致，以将正的结果呈现为使用者可见的加号（+）信号。