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公开(公告)号:US20080188723A1
公开(公告)日:2008-08-07
申请号:US11791924
申请日:2005-12-07
申请人: Jesper Svennin Kristensen , Klaus Gregorius , Casper Struve , John Myhre Frederiksen , Yihua Yu
发明人: Jesper Svennin Kristensen , Klaus Gregorius , Casper Struve , John Myhre Frederiksen , Yihua Yu
IPC分类号: A61B5/1455
CPC分类号: C08B37/0063 , A61B5/145 , A61B5/14532 , G01N33/54373 , G01N33/66
摘要: A sensor for the detection or measurement of carbohydrate analyte (such as glucose) in fluid comprises components of a competitive binding assay the readout of which is a detectable or measurable optical signal (such as FRET assay) retained by a material that permits diffusion of analyte but not the assay components, the assay components comprising: an animal lectin; and an analyte analogue capable of competing with analyte for binding to the lectin.
摘要翻译: 用于检测或测量流体中碳水化合物分析物(例如葡萄糖)的传感器包括竞争性结合测定的组分,其读出是可检测或可测量的光学信号(例如FRET测定),其由允许分析物扩散的材料保留 但不是测定组分,测定组分包含:动物凝集素; 以及能够与分析物竞争结合凝集素的分析物类似物。