公开(公告)号：US20090005733A1

公开(公告)日：2009-01-01

申请号：US11877967

申请日：2007-10-24

申请人： Jessica G. Chiu ,  Gregory Waimong Chan ,  Gabriel Asongwe ,  Robert C. Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Joan Bei ,  William E. Webler ,  Stephen G. Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark J. Bly ,  Thomas R. Hatten

发明人： Jessica G. Chiu ,  Gregory Waimong Chan ,  Gabriel Asongwe ,  Robert C. Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Joan Bei ,  William E. Webler ,  Stephen G. Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark J. Bly ,  Thomas R. Hatten

IPC分类号： A61M25/10 ,  A61M25/09

CPC分类号： A61M25/10 ,  A61M25/1002 ,  A61M2025/1052

摘要： Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial or co-linear lumen, a supporting mandrel, or an occlusion device at its distal end. Moreover, according to some embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.

摘要翻译： 实施例包括具有输送导管的输液阻塞系统，适于接收输送导管的引导导管，以及具有适于容纳在引导导管内的闭塞装置的导丝。 导管套件的引导导管可以在引导导管的远端处设置有闭塞装置。 输送导管可以具有附件腔，同轴或共线腔，支撑心轴或其远端处的闭塞装置。 此外，根据一些实施例，闭塞装置可以是具有内衬和不同材料外层的单一材料或复合球囊，高顺应性低压气球或限制颗粒通过但不限制的过滤装置 限制流体，如血液。 可以使用具有大体积和低体积注射器的充气装置来使气囊膨胀。

公开(公告)号：US07887661B2

公开(公告)日：2011-02-15

申请号：US11923258

申请日：2007-10-24

申请人： Jessica G. Chiu ,  Gregory Waimong Chan ,  Gabriel Asongwe ,  Robert C. Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Joan Bei ,  William E. Webler ,  Stephen G. Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark J. Bly ,  Thomas R. Hatten

发明人： Jessica G. Chiu ,  Gregory Waimong Chan ,  Gabriel Asongwe ,  Robert C. Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Joan Bei ,  William E. Webler ,  Stephen G. Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark J. Bly ,  Thomas R. Hatten

IPC分类号： B32B37/00

CPC分类号： A61M25/10 ,  A61M25/1002 ,  A61M2025/1052

摘要： Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial or co-linear lumen, a supporting mandrel, or an occlusion device at its distal end. Moreover, according to some embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.

摘要翻译： 实施例包括具有输送导管的输液阻塞系统，适于接收输送导管的引导导管，以及具有适于容纳在引导导管内的闭塞装置的导丝。 导管套件的引导导管可以在引导导管的远端处设置有闭塞装置。 输送导管可以具有附件腔，同轴或共线腔，支撑心轴或其远端处的闭塞装置。 此外，根据一些实施例，闭塞装置可以是具有内衬和不同材料外层的单一材料或复合球囊，高顺应性低压气球或限制颗粒通过但不限制的过滤装置 限制流体，如血液。 可以使用具有大体积和低体积注射器的充气装置来使气囊膨胀。

公开(公告)号：US20090018498A1

公开(公告)日：2009-01-15

申请号：US11923411

申请日：2007-10-24

申请人： Jessica G. Chiu ,  Gregory Waimong Chan ,  Gabriel Asongwe ,  Robert C. Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Joan Bei ,  William E. Webler ,  Stephen G. Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark J. Bly ,  Thomas R. Hatten

发明人： Jessica G. Chiu ,  Gregory Waimong Chan ,  Gabriel Asongwe ,  Robert C. Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Joan Bei ,  William E. Webler ,  Stephen G. Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark J. Bly ,  Thomas R. Hatten

IPC分类号： A61M29/02

CPC分类号： A61M25/10 ,  A61M25/1002 ,  A61M2025/1052

摘要： Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial or co-linear lumen, a supporting mandrel, or an occlusion device at its distal end. Moreover, according to some embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.

公开(公告)号：US09023010B2

公开(公告)日：2015-05-05

申请号：US11923068

申请日：2007-10-24

申请人： Jessica G. Chiu ,  Gregory Waimong Chan ,  Gabriel Asongwe ,  Robert C. Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Joan Bei ,  William E. Webler ,  Stephen G. Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark J. Bly ,  Thomas R. Hatten

发明人： Jessica G. Chiu ,  Gregory Waimong Chan ,  Gabriel Asongwe ,  Robert C. Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Joan Bei ,  William E. Webler ,  Stephen G. Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark J. Bly ,  Thomas R. Hatten

IPC分类号： A61M31/00 ,  A61M25/10

CPC分类号： A61M25/10 ,  A61M25/1002 ,  A61M2025/1052

摘要： Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial or co-linear lumen, a supporting mandrel, or an occlusion device at its distal end. Moreover, according to some embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.

摘要翻译： 实施例包括具有输送导管的输液阻塞系统，适于接收输送导管的引导导管，以及具有适于容纳在引导导管内的闭塞装置的导丝。 导管套件的引导导管可以在引导导管的远端处设置有闭塞装置。 输送导管可以具有附件腔，同轴或共线腔，支撑心轴或其远端处的闭塞装置。 此外，根据一些实施例，闭塞装置可以是具有内衬和不同材料外层的单一材料或复合球囊，高顺应性低压气球或限制颗粒通过但不限制的过滤装置 限制流体，如血液。 可以使用具有大体积和低体积注射器的充气装置来使气囊膨胀。

公开(公告)号：US20080041516A1

公开(公告)日：2008-02-21

申请号：US11923258

申请日：2007-10-24

申请人： Jessica Chiu ,  Gregory Chan ,  Gabriel Asongwe ,  Robert Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Bei ,  William Webler ,  Stephen Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark Bly ,  Thomas Hatten

发明人： Jessica Chiu ,  Gregory Chan ,  Gabriel Asongwe ,  Robert Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Bei ,  William Webler ,  Stephen Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark Bly ,  Thomas Hatten

IPC分类号： B29C53/60

CPC分类号： A61M25/10 ,  A61M25/1002 ,  A61M2025/1052

摘要： Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial or co-linear lumen, a supporting mandrel, or an occlusion device at its distal end. Moreover, according to some embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.

摘要翻译： 实施例包括具有输送导管的输液阻塞系统，适于接收输送导管的引导导管，以及具有适于容纳在引导导管内的闭塞装置的导丝。 导管套件的引导导管可以在引导导管的远端处设置有闭塞装置。 输送导管可以具有附件腔，同轴或共线腔，支撑心轴或其远端处的闭塞装置。 此外，根据一些实施例，闭塞装置可以是具有内衬和不同材料外层的单一材料或复合球囊，高顺应性低压气球或限制颗粒通过但不限制的过滤装置 限制流体，如血液。 可以使用具有大体积和低体积注射器的充气装置来使气囊膨胀。

公开(公告)号：US20050015048A1

公开(公告)日：2005-01-20

申请号：US10800323

申请日：2004-03-11

申请人： Jessica Chiu ,  Gregory Chan ,  Gabriel Asongwe ,  Robert Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Bei ,  William Webler ,  Stephen Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark Bly ,  Thomas Hatten

发明人： Jessica Chiu ,  Gregory Chan ,  Gabriel Asongwe ,  Robert Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Bei ,  William Webler ,  Stephen Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark Bly ,  Thomas Hatten

IPC分类号： A61F2/958 ,  A61M29/00

CPC分类号： A61M25/10 ,  A61M25/1002 ,  A61M2025/1052

摘要： Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial and/or co-linear lumen, a supporting mandrel, and/or an occlusion device at its distal end. Moreover, according to embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, and/or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.

摘要翻译： 实施例包括具有输送导管的输液阻塞系统，适于接收输送导管的引导导管，以及具有适于容纳在引导导管内的闭塞装置的导丝。 导管套件的引导导管可以在引导导管的远端处设置有闭塞装置。 输送导管可以在其远端具有附属腔，同轴和/或共线的腔，支撑心轴和/或闭塞装置。 此外，根据实施例，闭塞装置可以是具有不同材料的内衬和外层的单一材料或复合球囊，高顺应性低压气球和/或限制颗粒通过而过滤装置 不限制流体，如血液。 可以使用具有大体积和低体积注射器的充气装置来使气囊膨胀。

公开(公告)号：US20080103523A1

公开(公告)日：2008-05-01

申请号：US11923332

申请日：2007-10-24

申请人： Jessica Chiu ,  Gregory Chan ,  Gabriel Asongwe ,  Robert Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Bei ,  William Webler ,  Stephen Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark Bly ,  Thomas Hatten

发明人： Jessica Chiu ,  Gregory Chan ,  Gabriel Asongwe ,  Robert Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Bei ,  William Webler ,  Stephen Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark Bly ,  Thomas Hatten

IPC分类号： A61M29/00

CPC分类号： A61M25/10 ,  A61M25/1002 ,  A61M2025/1052

摘要： Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial or co-linear lumen, a supporting mandrel, or an occlusion device at its distal end. Moreover, according to some embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.

公开(公告)号：US20080103478A1

公开(公告)日：2008-05-01

申请号：US11923068

申请日：2007-10-24

申请人： Jessica Chiu ,  Gregory Chan ,  Gabriel Asongwe ,  Robert Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Bei ,  William Webler ,  Stephen Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark Bly ,  Thomas Hatten

发明人： Jessica Chiu ,  Gregory Chan ,  Gabriel Asongwe ,  Robert Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Bei ,  William Webler ,  Stephen Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark Bly ,  Thomas Hatten

IPC分类号： A61M31/00 ,  A61M25/10

CPC分类号： A61M25/10 ,  A61M25/1002 ,  A61M2025/1052

摘要： Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial or co-linear lumen, a supporting mandrel, or an occlusion device at its distal end. Moreover, according to some embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.

公开(公告)号：US11125213B1

公开(公告)日：2021-09-21

申请号：US16941457

申请日：2020-07-28

申请人： Chuang Yu ,  Zexiang Wu ,  Wenhao Gu ,  Bo Li ,  Yan Shen ,  Jinjing Ly

发明人： Chuang Yu ,  Zexiang Wu ,  Wenhao Gu ,  Bo Li ,  Yan Shen ,  Jinjing Ly

IPC分类号： F03D9/00 ,  F03D9/46 ,  A01G25/00 ,  H02K7/18 ,  F03B17/00

摘要： A road traffic and wind energy cogeneration system, comprising an energy conversion device and a road bearing mechanism, wherein the road bearing mechanism has a container, the container includes a case and a top cover; a piston is disposed in the case; an elastic chamber is disposed between the piston and a bottom wall of the case; the elastic chamber is filled with liquid; a guide column is fixed to the piston; the guide column penetrates upwards through the top cover to be fixed to a road pressure plate; an elastic mechanism is disposed between the piston and case bottom; an air cavity is formed between the top cover and piston; tire air cavity is connected to the wind power installation through the conduit; the elastic chamber is connected to a water flow power installation through the conduit.

公开(公告)号：US20140194418A1

公开(公告)日：2014-07-10

申请号：US13979387

申请日：2012-01-20

申请人： Anil Vasudevan ,  Thomas Dale Penning ,  Huanming Chen ,  Bo Liang ,  Shaohui Wang ,  Fengchun Wu ,  Yan Shen ,  Cuihua Liu ,  Zhenguang Zou ,  Marina Pliushchev

发明人： Anil Vasudevan ,  Thomas Dale Penning ,  Huanming Chen ,  Bo Liang ,  Shaohui Wang ,  Fengchun Wu ,  Yan Shen ,  Cuihua Liu ,  Zhenguang Zou ,  Marina Pliushchev

IPC分类号： C07D519/00 ,  C07D471/04 ,  C07D487/04

CPC分类号： C07D519/00 ,  A61K31/4353 ,  C07D471/04 ,  C07D487/04

摘要： Compounds of formula (I) or pharmaceutical acceptable salts are provided, wherein X1˜X5, R1˜R3, A, B, Z and n are defined in the description. And compositions containing said compounds, and the uses for inhibitors of kinases such as ALK, and the uses for treating cancer thereof are provided.

摘要翻译： 提供式（I）化合物或药学上可接受的盐，其中X 1，X 5，R 1〜R 3，A，B，Z和n在说明书中定义。 并提供含有所述化合物的组合物，以及用于激酶例如ALK的用途及其用于治疗癌症的用途。