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公开(公告)号:US20200255388A1
公开(公告)日:2020-08-13
申请号:US16499050
申请日:2018-03-29
申请人: Jia ZHOU , Zhiqing Liu , Na Ye , Fang Mei , Xiaodong Cheng
发明人: Jia ZHOU , Zhiqing Liu , Na Ye , Fang Mei , Xiaodong Cheng
IPC分类号: C07D261/08 , C07D261/20 , A61P31/04
摘要: Embodiments are directed to a series of novel EPAC antagonists that are designed, synthesized and evaluated in an effort to develop diversified analogues based on the scaffold of the previously identified high-throughput (HTS) hit ESI-09.
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公开(公告)号:US11124489B2
公开(公告)日:2021-09-21
申请号:US16499050
申请日:2018-03-29
申请人: Jia Zhou , Zhiqing Liu , Na Ye , Fang Mei , Xiaodong Cheng
发明人: Jia Zhou , Zhiqing Liu , Na Ye , Fang Mei , Xiaodong Cheng
IPC分类号: C07D261/08 , C07D261/20 , A61P31/04 , A61P31/12
摘要: Embodiments are directed to a series of novel EPAC antagonists that are designed, synthesized and evaluated in an effort to develop diversified analogues based on the scaffold of the previously identified high-throughput (HTS) hit ESI-09.
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