AraC in combination with a cytokine-secreting cell and methods of use thereof
    1.
    发明申请
    AraC in combination with a cytokine-secreting cell and methods of use thereof 审中-公开
    AraC与细胞因子分泌细胞的组合及其使用方法

    公开(公告)号:US20080267935A1

    公开(公告)日:2008-10-30

    申请号:US12080719

    申请日:2008-04-04

    摘要: The present invention provides improved method of cancer therapy in a mammal. More particularly, the invention is concerned with systems comprising cytosine arabinoside (AraC) and a cytokine-expressing cancer immunotherapy composition and methods of administering the combination to cancer patients in order to generate an immune response against the cancer and provide treatment with therapeutic efficacy that is an improvement relative to administration of AraC or the cytokine-expressing cancer immunotherapy composition alone as a monotherapy.

    摘要翻译: 本发明提供了哺乳动物癌症治疗的改进方法。 更具体地,本发明涉及包含胞嘧啶阿拉伯糖苷(AraC)和表达细胞因子的癌症免疫治疗组合物的系统以及向癌症患者施用组合的方法,以产生针对癌症的免疫应答,并提供具有治疗功效的治疗 相对于单独使用AraC或单独使用细胞因子的癌症免疫治疗组合物而言,其改善。