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公开(公告)号:US20110150886A1
公开(公告)日:2011-06-23
申请号:US12988135
申请日:2009-04-17
申请人: Jill Caswell , Shane Olwill , James Johnston , Richard Buick , Thomas Jaquin , Declan Doherty , Christopher Scott
发明人: Jill Caswell , Shane Olwill , James Johnston , Richard Buick , Thomas Jaquin , Declan Doherty , Christopher Scott
IPC分类号: A61K39/395 , A61K31/7088 , A61P35/00 , C07K16/18 , C07H21/04
CPC分类号: C07K16/22 , A61K39/39558 , A61K2039/505 , C07K16/2863 , C07K2317/31 , C07K2317/33 , C07K2317/73 , C07K2317/74 , A61K2300/00
摘要: Described are cross-specific antibody molecules with binding specificity for both AREG and HBEGF. The antibody molecules may be used in methods of treatment of cancer and diseases associated with angiogenesis.
摘要翻译: 描述了对AREG和HBEGF具有结合特异性的交叉特异性抗体分子。 抗体分子可用于治疗癌症和与血管发生相关的疾病的方法。
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公开(公告)号:US08846868B2
公开(公告)日:2014-09-30
申请号:US12988135
申请日:2009-04-17
申请人: Jill Caswell , Shane Olwill , James Johnston , Richard Buick , Thomas Jaquin , Declan Doherty , Christopher Scott
发明人: Jill Caswell , Shane Olwill , James Johnston , Richard Buick , Thomas Jaquin , Declan Doherty , Christopher Scott
CPC分类号: C07K16/22 , A61K39/39558 , A61K2039/505 , C07K16/2863 , C07K2317/31 , C07K2317/33 , C07K2317/73 , C07K2317/74 , A61K2300/00
摘要: Described are cross-specific antibody molecules with binding specificity for both AREG and HBEGF. The antibody molecules may be used in methods of treatment of cancer and diseases associated with angiogenesis.
摘要翻译: 描述了对AREG和HBEGF具有结合特异性的交叉特异性抗体分子。 抗体分子可用于治疗癌症和与血管发生相关的疾病的方法。
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