PRODUCTION METHOD FOR 4,4'-BIS(ALKYLAMINO) DIPHENYLAMINE
    1.
    发明申请
    PRODUCTION METHOD FOR 4,4'-BIS(ALKYLAMINO) DIPHENYLAMINE 审中-公开
    4,4'-双(二氨基)二苯胺的生产方法

    公开(公告)号:US20120197044A1

    公开(公告)日:2012-08-02

    申请号:US13502052

    申请日:2010-09-30

    IPC分类号: C07C209/36

    CPC分类号: C07C209/36 C07C211/54

    摘要: The present invention relates to a production method for 4,4′-bis(alkylamino)diphenylamine, and more specifically relates to a method in which 4,4′-dinitrodiphenylamine (4,4′-DNDPA) is produced by reacting urea with nitrobenzene in the presence of a polar organic solvent and a base catalyst, and then the 4,4′-bis(alkylamino)diphenylamine (4,4′-BAADA) is produced by subjecting the 4,4′-DNDPA and a ketone to hydrogenation in the presence of a hydrogenation catalyst.

    摘要翻译: 本发明涉及一种4,4'-双(烷基氨基)二苯胺的制备方法,更具体地说涉及一种方法,其中4,4'-二硝基二苯胺(4,4'-DNDPA)是通过尿素与硝基苯 在极性有机溶剂和碱催化剂存在下,然后通过使4,4'-DNDPA和酮氢化得到4,4'-双(烷基氨基)二苯胺(4,4'-BAADA) 在氢化催化剂的存在下。

    Composition comprising starch or dietary fiber from gramineae plant for prevention and treatment of ischemic diseases and degenerative brain disease
    3.
    发明授权
    Composition comprising starch or dietary fiber from gramineae plant for prevention and treatment of ischemic diseases and degenerative brain disease 有权
    组合物,其包含来自禾本科植物的淀粉或膳食纤维,用于预防和治疗缺血性疾病和退行性脑病

    公开(公告)号:US08211483B2

    公开(公告)日:2012-07-03

    申请号:US12666969

    申请日:2008-07-04

    CPC分类号: A61K31/715 A61K31/718

    摘要: The present invention relates to a composition comprising a starch or total dietary fiber which improves the cell viability, specifically, the inventive starch and total dietary fiber isolated from the extract of Gramineae plant and the components therefrom improved the cell viability when the cells were incubated under hypoxic condition, or in the presence of beta-amyloid and 6-hydroxydopamine treatment, as well as prevented and treated myocardiac infarction, cerebral infarction and vascular dementia, or alleviated memory loss, all of which were proven using rats as the respective animal models. Therefore, they can be used as therapeutics or health care food for preventing and treating ischemic diseases or degenerative brain diseases.

    摘要翻译: 本发明涉及一种组合物,其包含改善细胞存活力的淀粉或总膳食纤维,具体地,本发明的淀粉和从禾本科植物提取物中分离的总膳食纤维,并且其组分在细胞孵育时改善了细胞活力 或在β-淀粉样蛋白和6-羟基多巴胺治疗的存在下,以及预防和治疗的心肌梗死,脑梗死和血管性痴呆,或缓解记忆丧失,所有这些都使用大鼠作为相应的动物模型。 因此,它们可以用作预防和治疗缺血性疾病或退行性脑疾病的治疗剂或保健食品。