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公开(公告)号:US07256024B2
公开(公告)日:2007-08-14
申请号:US10891888
申请日:2004-11-18
申请人: Jingfang Q. Cutrone , Lyndon M. Foster , Kimberly D. Krampitz , Stephen W. Mamber , Grace A. McClure , Todd C. Peterson , Lisa C. Rupar , Katie A. Thompson
发明人: Jingfang Q. Cutrone , Lyndon M. Foster , Kimberly D. Krampitz , Stephen W. Mamber , Grace A. McClure , Todd C. Peterson , Lisa C. Rupar , Katie A. Thompson
CPC分类号: C12N1/20 , A61K35/742 , C12P7/62 , C12R1/465
摘要: A novel tyrosyl diester antibiotic is obtained from fermentation of a recombinant strain of Streptomyces lividans designated Stretomyces lividans WD 15684 (ATCC-202143). The new antibiotic, designated tyrissamycin, exhibits antibacterial activity, particularly against gram-positive bacteria.
摘要翻译: 一种新型的酪氨酰二酯抗生素是从称为Streptomyces lividans WD 15684(ATCC-202143)的重组链霉链霉菌株发酵获得的。 新的抗生素,称为泰利沙霉素,具有抗菌活性,特别是抗革兰氏阳性菌。
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公开(公告)号:US06291461B1
公开(公告)日:2001-09-18
申请号:US09391131
申请日:1999-09-07
IPC分类号: A61K31495
CPC分类号: C07D471/18 , C07D519/00
摘要: The novel antitumor antibiotics designated stephacidin A and stephacidin B are produced by fermentation of Aspergillus ochraceus ATCC-74432. The antibiotics inhibit the growth of mammalian tumors, including particularly prostate carcinoma.
摘要翻译: 命名为杀青霉素A和间歇杀菌素B的新型抗肿瘤抗生素通过发酵赭曲霉ATCC-74432产生。 抗生素抑制哺乳动物肿瘤的生长,特别是前列腺癌。
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