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公开(公告)号：US20170044212A1
公开(公告)日：2017-02-16
申请号：US15236055
申请日：2016-08-12
申请人： Jingyi Wang
发明人： Jingyi Wang , Jianling Zuo , Xiaoliang Lv , Tan Zhang
摘要： The present invention provides a compound (I) for treating sequelae of ischemic cerebral stroke: H—(NH—CHR1—CO)—(NH—CHR2—CO)—(NH—CHR3—CO)—(NH—CHR4—CO)—(NH—CHR5—CO)—(NH—CHR6—CO)—(NH—CHR7—CO)—OH (I) or a pharmaceutically acceptable salt thereof, wherein R1-R7 are defined herein. The present invention also provides a pharmaceutical composition comprising said compound and use of the same in the manufacture of a medicament for treating sequelae of ischemic cerebral stroke. The compound and pharmaceutical composition according to the present invention have good pharmacological activities so that they are able to improve significantly the symptom of sequelae of ischemic cerebral stroke.
摘要翻译： 或其药学上可接受的盐，其中R 1 -R 7在本文中定义。 本发明还提供了包含所述化合物的药物组合物及其在制备用于治疗缺血性脑卒中后遗症的药物中的用途。 根据本发明的化合物和药物组合物具有良好的药理活性，使得它们能够显着改善缺血性脑卒中后遗症状。
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公开(公告)号：US10647745B2
公开(公告)日：2020-05-12
申请号：US16059174
申请日：2018-08-09
申请人： Jingyi Wang
发明人： Jingyi Wang , Jianling Zuo , Xiaoliang Lv , Tan Zhang
摘要： The present invention provides a compound (I) for treating sequelae of ischemic cerebral stroke: H—(NH—CHR1—CO)—(NH—CHR2—CO)—(NH—CHR3—CO)—(NH—CHR4—CO)—(NH—CHR5—CO)—(NH—CHR6—CO)—(NH—CHR7—CO)—OH (I) or a pharmaceutically acceptable salt thereof, wherein R1-R7 are defined herein. The present invention also provides a pharmaceutical composition comprising said compound and use of the same in the manufacture of a medicament for treating sequelae of ischemic cerebral stroke. The compound and pharmaceutical composition according to the present invention have good pharmacological activities so that they are able to improve significantly the symptom of sequelae of ischemic cerebral stroke.
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