Substituted pyrrolo[2,3-d]pyrimidine derivatives useful in cancer treatment
    3.
    发明授权
    Substituted pyrrolo[2,3-d]pyrimidine derivatives useful in cancer treatment 失效
    用于癌症治疗的取代的吡咯并[2,3-d]嘧啶衍生物

    公开(公告)号:US07595325B2

    公开(公告)日:2009-09-29

    申请号:US11140411

    申请日:2005-05-27

    CPC分类号: C07D487/04

    摘要: The invention relates to compounds of the formula 1 or a pharmaceutically acceptable salt, prodrug, solvate or hydrate thereof, wherein L, R1, R2, R3 and R4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating abnormal cell growth, such as cancer in a mammal by administering the compounds of formula 1.

    摘要翻译: 本发明涉及式1化合物或其药学上可接受的盐,前药,溶剂合物或水合物,其中L,R 1,R 2,R 3和R 4如本文所定义。 本发明还涉及含有式1化合物的药物组合物和通过施用式1化合物治疗哺乳动物异常细胞生长如癌症的方法。