POLYMORPHS OF (S)-1-(4,4,6,6,6-PENTADEUTERO-5-HYDROXYHEXYL)-3-7-DIMETHYL-1H-PURINE-2,6(3H,7H)-DIONE
    1.
    发明申请
    POLYMORPHS OF (S)-1-(4,4,6,6,6-PENTADEUTERO-5-HYDROXYHEXYL)-3-7-DIMETHYL-1H-PURINE-2,6(3H,7H)-DIONE 审中-公开
    (S)-1-(4,4,6,6,6-苯并二氢-5-羟基己基)-3-7-二甲基-1H-嘌呤-2,6(3H,7H) - 酮的多聚

    公开(公告)号:US20130324564A1

    公开(公告)日:2013-12-05

    申请号:US13820022

    申请日:2011-09-01

    IPC分类号: C07D473/10

    摘要: The present invention provides individual crystalline polymorphs of (S)-1-(4,4,6, 6,6-pentadeutero-5-hydroxy-hexyl)-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione designated Form 1, Form 2, Form 3 and Form 4. Each polymorph disclosed herein is characterized according to one or more of (a) powder X-ray diffraction data (“XRPD”); (b) differential scanning calorimetry (“DSC”); and (e) thermo gravimetric analysis (TGA).

    摘要翻译: 本发明提供了(S)-1-(4,4,6,6,6-五氘代-5-羟基 - 己基)-3,7-二甲基-1H-嘌呤-2,6(3H, 7H) - 二酮,命名为Form 1,Form 2,Form 3和Form 4.本文公开的每个多晶型物根据(a)粉末X射线衍射数据(“XRPD”)中的一种或多种进行表征。 (b)差示扫描量热法(“DSC”); 和(e)热重分析(TGA)。