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公开(公告)号:US08450333B2
公开(公告)日:2013-05-28
申请号:US12028536
申请日:2008-02-08
申请人: Jodi Nunnari , Ann Cassidy-Stone , Mark Kurth
发明人: Jodi Nunnari , Ann Cassidy-Stone , Mark Kurth
IPC分类号: A01N43/54 , A61K31/517 , C07D239/72
CPC分类号: C07D239/95 , C07D277/36 , C07D277/38 , C07D409/14 , C07D498/04 , C07D513/04
摘要: The present invention provides compounds capable of regulating apoptosis, e.g., via regulating mitochondrial fission or fusion. The present invention also provides methods of screening for compounds capable of regulating apoptosis and methods of treating conditions association with apoptosis.
摘要翻译: 本发明提供能够调节凋亡的化合物,例如通过调节线粒体裂变或融合。 本发明还提供了筛选能够调节凋亡的化合物的方法以及治疗与凋亡相关的病症的方法。
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公开(公告)号:US20050038051A1
公开(公告)日:2005-02-17
申请号:US10865542
申请日:2004-06-09
申请人: Jodi Nunnari , Ann Cassidy-Stone , Mark Kurth
发明人: Jodi Nunnari , Ann Cassidy-Stone , Mark Kurth
IPC分类号: A61K31/517 , C07D239/95 , C07D277/36 , C07D277/38 , C07D409/14 , C07D498/04 , C07D513/04 , C07K20060101 , C07D43/02
CPC分类号: C07D239/95 , C07D277/36 , C07D277/38 , C07D409/14 , C07D498/04 , C07D513/04
摘要: The present invention provides compounds capable of regulating apoptosis, e.g., via regulating mitochondrial fission or fusion. The present invention also provides methods of screening for compounds capable of regulating apoptosis and methods of treating conditions association with apoptosis.
摘要翻译: 本发明提供能够调节凋亡的化合物,例如通过调节线粒体裂变或融合。 本发明还提供了筛选能够调节凋亡的化合物的方法以及治疗与凋亡相关的病症的方法。
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公开(公告)号:US20080287473A1
公开(公告)日:2008-11-20
申请号:US12028536
申请日:2008-02-08
申请人: Jodi Nunnari , Ann Cassidy-Stone , Mark Kurth
发明人: Jodi Nunnari , Ann Cassidy-Stone , Mark Kurth
IPC分类号: A61K31/517 , C07D239/95
CPC分类号: C07D239/95 , C07D277/36 , C07D277/38 , C07D409/14 , C07D498/04 , C07D513/04
摘要: The present invention provides compounds capable of regulating apoptosis, e.g., via regulating mitochondrial fission or fusion. The present invention also provides methods of screening for compounds capable of regulating apoptosis and methods of treating conditions association with apoptosis.
摘要翻译: 本发明提供能够调节凋亡的化合物,例如通过调节线粒体裂变或融合。 本发明还提供了筛选能够调节凋亡的化合物的方法以及治疗与凋亡相关的病症的方法。
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