公开(公告)号：US4197250A

公开(公告)日：1980-04-08

申请号：US887219

申请日：1978-03-16

申请人： Joerg Redeker ,  Heinrich Hiller ,  Enno Spohler

发明人： Joerg Redeker ,  Heinrich Hiller ,  Enno Spohler

IPC分类号： C09B1/503 ,  B01F17/42 ,  C07C20060101 ,  C07C225/36 ,  C09B1/50 ,  C07C97/26

CPC分类号： C09B1/503

摘要： In a process for the manufacture of 1-amino-2-bromo-4-hydroxyanthraquinone by hydroxylating previously prepared and isolated 1-amino-2,4-dibromoanthraquinone in sulfuric acid in the presence of boric acid at from 110.degree. to 130.degree. C., the improvememt that 1-aminoanthraquinone is brominated (from 1.5 to 2.1 moles of bromine per mole) in sulfuric acid of from 50 to 85 percent strength at from 80.degree. to 130.degree. C., the reaction mixture is brought to a concentration of from 96 percent strength sulfuric acid to 5 percent strength oleum by adding oleum; and the dibromo compound is then hydroxylated in the presence of boric acid. Very pure 1-amino-2-bromo-4-hydroxyanthraquinone, which can be used for all purposes, is obtained in a high yield.

摘要翻译： 在制备1-氨基-2-溴-4-羟基蒽醌的方法中，通过在110-130℃的硼酸存在下，在硫酸中羟化预先制备和分离的1-氨基-2,4-二溴蒽醌 在80至130℃下，将1-氨基蒽醌溴化（每摩尔1.5至2.1摩尔溴）在硫酸中的强度提高50至85％，将反应混合物的浓度 通过加入发烟硫酸，从96％的强度硫酸到5％的发烟硫酸; 然后在硼酸的存在下将二溴化合物羟化。 以高产率获得可用于所有目的的非常纯的1-氨基-2-溴-4-羟基蒽醌。