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公开(公告)号：US07858304B2
公开(公告)日：2010-12-28
申请号：US11450973
申请日：2006-06-09
CPC分类号： G01N33/57484 , C12N15/1003 , C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/158 , C12Q2600/16 , G01N33/57415
摘要： The invention concerns sensitive methods to measure mRNA levels in biopsied tumor tissues, including archived paraffin-embedded biopsy material. The invention also concerns breast cancer gene sets important in the diagnosis and treatment of breast cancer, and methods for assigning the most optimal treatment options to breast cancer patient based upon knowledge derived from gene expression studies.
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公开(公告)号：US07081340B2
公开(公告)日：2006-07-25
申请号：US10388360
申请日：2003-03-12
CPC分类号： G01N33/57484 , C12N15/1003 , C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/158 , C12Q2600/16 , G01N33/57415
摘要： The invention concerns sensitive methods to measure mRNA levels in biopsied tumor tissues, including archived paraffin-embedded biopsy material. Th invention also concerns breast cancer gene sets important in the diagnosis and treatment of breast cancer, and methods for assigning the most optimal treatment options to breast cancer patient based upon knowledge derived from gene expression studies.
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公开(公告)号：US08071286B2
公开(公告)日：2011-12-06
申请号：US11450964
申请日：2006-06-09
CPC分类号： G01N33/57484 , C12N15/1003 , C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/158 , C12Q2600/16 , G01N33/57415
摘要： The invention concerns sensitive methods to measure mRNA levels in biopsied tumor tissues, including archived paraffin-embedded biopsy material. The invention also concerns breast cancer gene sets important in the diagnosis and treatment of breast cancer, and methods for assigning the most optimal treatment options to breast cancer patient based upon knowledge derived from gene expression studies.
摘要翻译： 本发明涉及测量活检肿瘤组织中的mRNA水平的敏感方法，包括归档石蜡包埋的活检材料。 本发明还涉及在乳腺癌诊断和治疗中重要的乳腺癌基因集，以及基于从基因表达研究获得的知识为乳腺癌患者分配最佳治疗选择的方法。
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公开(公告)号：US10241114B2
公开(公告)日：2019-03-26
申请号：US11450896
申请日：2006-06-09
IPC分类号： C12Q1/68 , G01N33/574 , C12N15/10 , C12Q1/6886
摘要： The invention concerns sensitive methods to measure mRNA levels in biopsied tumor tissues, including archived paraffin-embedded biopsy material. The invention also concerns breast cancer gene sets important in the diagnosis and treatment of breast cancer, and methods for assigning the most optimal treatment options to breast cancer patient based upon knowledge derived from gene expression studies.
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公开(公告)号：US07838224B2
公开(公告)日：2010-11-23
申请号：US11450962
申请日：2006-06-09
CPC分类号： G01N33/57484 , C12N15/1003 , C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/158 , C12Q2600/16 , G01N33/57415
摘要： The invention concerns sensitive methods to measure mRNA levels in biopsied tumor tissues, including archived paraffin-embedded biopsy material. The invention also concerns breast cancer gene sets important in the diagnosis and treatment of breast cancer, and methods for assigning the most optimal treatment options to breast cancer patient based upon knowledge derived from gene expression studies.
摘要翻译： 本发明涉及测量活检肿瘤组织中的mRNA水平的敏感方法，包括归档石蜡包埋的活检材料。 本发明还涉及在乳腺癌诊断和治疗中重要的乳腺癌基因集，以及基于从基因表达研究获得的知识为乳腺癌患者分配最佳治疗选择的方法。
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公开(公告)号：US20100209920A1
公开(公告)日：2010-08-19
申请号：US12616039
申请日：2009-11-10
IPC分类号： C12Q1/68
CPC分类号： G01N33/57484 , C12N15/1003 , C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/158 , C12Q2600/16 , G01N33/57415
摘要： The invention concerns sensitive methods to measure mRNA levels in biopsied tumor tissues, including archived paraffin-embedded biopsy material. The invention also concerns breast cancer gene sets important in the diagnosis and treatment of breast cancer, and methods for assigning the most optimal treatment options to breast cancer patient based upon knowledge derived from gene expression studies.
摘要翻译： 本发明涉及测量活检肿瘤组织中的mRNA水平的敏感方法，包括归档石蜡包埋的活检材料。 本发明还涉及在乳腺癌诊断和治疗中重要的乳腺癌基因集，以及基于从基因表达研究获得的知识为乳腺癌患者分配最佳治疗选择的方法。
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公开(公告)号：US20080182255A1
公开(公告)日：2008-07-31
申请号：US11931441
申请日：2007-10-31
CPC分类号： G01N33/57484 , C12N15/1003 , C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/158 , C12Q2600/16 , G01N33/57415
摘要： The invention concerns sensitive methods to measure mRNA levels in biopsied tumor tissues, including archived paraffin-embedded biopsy material. The invention also concerns breast cancer gene sets important in the diagnosis and treatment of breast cancer, and methods for assigning the most optimal treatment options to breast cancer patient based upon knowledge derived from gene expression studies.
摘要翻译： 本发明涉及测量活检肿瘤组织中的mRNA水平的敏感方法，包括归档石蜡包埋的活检材料。 本发明还涉及在乳腺癌诊断和治疗中重要的乳腺癌基因集，以及基于从基因表达研究获得的知识为乳腺癌患者分配最佳治疗选择的方法。
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公开(公告)号：US20100222229A1
公开(公告)日：2010-09-02
申请号：US12478632
申请日：2009-06-04
CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/158
摘要： The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.
摘要翻译： 本发明提供了在乳腺癌的诊断和/或预后中重要的基因组。
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公开(公告)号：US08741605B2
公开(公告)日：2014-06-03
申请号：US13473526
申请日：2012-05-16
IPC分类号： C12P19/34
CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/158
摘要： The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.
摘要翻译： 本发明提供了在乳腺癌的诊断和/或预后中重要的基因组。
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公开(公告)号：US20120225433A1
公开(公告)日：2012-09-06
申请号：US13473526
申请日：2012-05-16
IPC分类号： C12Q1/68 , G01N33/573 , G01N33/566
CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/158
摘要： The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.
摘要翻译： 本发明提供了在乳腺癌的诊断和/或预后中重要的基因组。
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