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公开(公告)号:US20080227776A1
公开(公告)日:2008-09-18
申请号:US12056245
申请日:2008-03-26
IPC分类号: A61K31/5365 , A61K31/505 , A61K31/44 , C07D239/02 , A61P29/00 , A61P19/02 , A61P25/00 , C07D213/02 , A61K31/4375
CPC分类号: A61K31/4375 , A61K31/44 , A61K31/505 , A61K31/5365
摘要: Methods and compounds for the treatment or prevention of oxidative damage in a mammalian subject. The treatment and/or prevention may be on inhibiting heme-induced lipid peroxidation. Also discloses are methods and compounds for treating or preventing isoprostane-mediated tissue damage.
摘要翻译: 用于治疗或预防哺乳动物受试者的氧化损伤的方法和化合物。 治疗和/或预防可能是抑制血红素诱导的脂质过氧化。 还公开了用于治疗或预防异前列烷介导的组织损伤的方法和化合物。
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公开(公告)号:US08367669B2
公开(公告)日:2013-02-05
申请号:US12056245
申请日:2008-03-26
IPC分类号: A01N43/58 , A01N43/54 , A01N43/40 , A01N43/42 , A61K31/50 , A61K31/435 , A61K31/44 , C07D239/42 , C07D401/04
CPC分类号: A61K31/4375 , A61K31/44 , A61K31/505 , A61K31/5365
摘要: Methods and compounds for the treatment or prevention of oxidative damage in a mammalian subject. The treatment and/or prevention may be on inhibiting heme-induced lipid peroxidation. Also discloses are methods and compounds for treating or preventing isoprostane-mediated tissue damage.
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