公开(公告)号：US5112999A

公开(公告)日：1992-05-12

申请号：US580711

申请日：1990-09-11

申请人： John A. Osborn ,  You P. N. C. Chan ,  Hans-Ulrich Blaser ,  Felix Spindler

发明人： John A. Osborn ,  You P. N. C. Chan ,  Hans-Ulrich Blaser ,  Felix Spindler

IPC分类号： B01J31/22 ,  B01J31/24 ,  C07B43/04 ,  C07B53/00 ,  C07B61/00 ,  C07C209/44 ,  C07C209/52 ,  C07C211/03 ,  C07C211/21 ,  C07C213/02 ,  C07C217/08 ,  C07C231/16 ,  C07F15/00

CPC分类号： C07F15/004

摘要： Compounds of general formula I or Ia ##STR1## or mixtures thereof, wherein the groups P-L-P are a ligand from the group comprising diphosphine and diphosphinite, in which the secondary phosphine groups or phosphinite groups P are coupled via 2 to 4 C atoms, and which form a 5-, 6- or 7-membered ring with the Ir atoms, X, X.sup.1, X.sup.2, X.sup.3, X.sup.4, X.sup.5 and X.sup.6 independently of the others are Cl, Br or I, or X.sup.1 and X.sup.6 and H and X.sup.2, X.sup.3, X.sup.4 and X.sup.5 independently of the others are Cl, Br or I, or X.sup.1 and X.sup.5 and H and X.sup.2, X.sup.3, X.sup.4 and X.sup.6 independently of the others are Cl, Br or I, and M.sup..sym. is an alkali metal cation or quaternary ammonium. The compounds are suitable as homogeneous catalysts for the (preferably) asymmetric hydrogenation of N-substituted imines to secondary amines.

摘要翻译： （Ⅰ）或其混合物的通式I或Ia化合物或其混合物，其中基团PLP是来自包括二膦和二磷酸盐的基团的配体，其中仲膦基团或次膦酸基团P连接 通过2至4个C原子，并且与Ir原子形成5-，6-或7-元环，其中X，X 1，X 2，X 3，X 4，X 5和X 6独立地为Cl，Br或I， 或者X 1和X 6以及H和独立地为Cl，Br或I的X 1，X 3，X 4和X 5分别为Cl，Br或I，或者X 1和X 5以及H和独立地为Cl，Br或I的X 2，X 3，X 4和X 6， M（+）是碱金属阳离子或季铵。 该化合物适合用作（优选）N-取代亚胺对仲胺的不对称氢化的均相催化剂。