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公开(公告)号:US20070239707A1
公开(公告)日:2007-10-11
申请号:US11731751
申请日:2007-03-30
申请人: John Collins , Jerome Verlin , Can Akyuz , Stuart Donnelly
发明人: John Collins , Jerome Verlin , Can Akyuz , Stuart Donnelly
IPC分类号: G06F17/30
CPC分类号: G06F17/30705
摘要: A method of locating relevant documents wherein documents are given a fingerprint comprising weights associated with particular topic categories of a classification system, each weight representing a degree to which the document relates to the particular topic category, a first piece of text is identified and given a fingerprint comprising a list of other weights associated with similar topic categories, the other weights representing a degree to which the first piece of text relates to the particular topic category. All or a portion of the universe of documents is searched by comparing the fingerprint for the first piece of text with the fingerprint for each document. You select those documents whose fingerprints have a predetermined degree of mathematical overlap with the fingerprint of the first piece of text. A user fingerprint of the user's recently accessed texts can be used in place of the first piece of text.
摘要翻译: 一种定位相关文件的方法,其中文档被给予包括与分类系统的特定主题类别相关联的权重的指纹,每个权重表示文档与特定主题类别相关的程度,第一文本被识别并给出 指纹包括与类似主题类别相关联的其他权重的列表,其他权重表示第一文本与特定主题类别相关的程度。 通过将第一文本的指纹与每个文档的指纹进行比较来搜索文档的全部或一部分。 您可以选择那些指纹与第一条文本的指纹具有预定数学重叠程度的文档。 可以使用用户最近访问的文本的用户指纹来代替第一文本。
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公开(公告)号:US20050064510A1
公开(公告)日:2005-03-24
申请号:US10797551
申请日:2004-03-10
申请人: Can Akyuz , D. Annis , William Lee , Gergely Makara , Ciamac Moallemi , Huw Nash , Zhongli Zheng
发明人: Can Akyuz , D. Annis , William Lee , Gergely Makara , Ciamac Moallemi , Huw Nash , Zhongli Zheng
IPC分类号: C12Q1/68 , G01N20060101 , G01N33/53 , G01N33/566
CPC分类号: G01N33/6848 , C07D307/68 , C07D401/12 , C07D405/14 , C07D413/10
摘要: Methods for the analysis of receptor-ligand pairs are herein described. The methods can provide information about the binding affinity of a ligand to a receptor or can provide information about the binding kinetics of a ligand to a receptor. In some instances, the methods provide a very general system for evaluating and/or optimizing receptor-ligand interactions, which can be applied to a variety of types of receptor-ligand interactions, for example protein-small molecule interactions.
摘要翻译: 本文描述了受体 - 配体对分析方法。 该方法可以提供关于配体对受体的结合亲和力的信息,或者可以提供关于配体与受体的结合动力学的信息。 在某些情况下,该方法提供了用于评估和/或优化受体 - 配体相互作用的非常通用的系统,其可以应用于多种类型的受体 - 配体相互作用,例如蛋白质 - 小分子相互作用。
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