公开(公告)号：US11020386B2

公开(公告)日：2021-06-01

申请号：US15431624

申请日：2017-02-13

申请人： Albany Molecular Research, Inc. ,  John K. Thottathil

发明人： Matthew Surman ,  Kathryn Golden ,  Paolo Pasetto ,  Xiaomin Jin ,  Xiaowu Jiang ,  Fatoumata Camara ,  John K. Thottathil

IPC分类号： A61K31/485 ,  C07D489/08 ,  A61K47/54

摘要： Abuse-resistant opioid compounds, drug delivery systems, pharmaceutical compositions comprising an opioid covalently bound to a chemical moiety are provided. Methods of delivering an active ingredient to a subject and methods of preventing opioid abuse are also provided.

公开(公告)号：US20170157116A1

公开(公告)日：2017-06-08

申请号：US15431572

申请日：2017-02-13

申请人： John K. Thottathil ,  Albany Molecular Research, Inc.

发明人： Matthew Surman ,  John K. Thottathil ,  Kathryn Golden ,  Paolo Pasetto ,  Xiaomin Jin ,  Xiaowu Jiang ,  Fatoumata Camara

IPC分类号： A61K31/485 ,  C07D489/08

CPC分类号： A61K31/485 ,  A61K47/542 ,  C07D489/08

摘要： Abuse-resistant opioid compounds, drug delivery systems, pharmaceutical compositions comprising an opioid covalently bound to a chemical moiety are provided. Methods of delivering an active ingredient to a subject and methods of preventing opioid abuse are also provided.

公开(公告)号：US10695342B2

公开(公告)日：2020-06-30

申请号：US15431572

申请日：2017-02-13

申请人： Albany Molecular Research, Inc. ,  John K. Thottathil

发明人： Matthew Surman ,  John K. Thottathil ,  Kathryn Golden ,  Paolo Pasetto ,  Xiaomin Jin ,  Xiaowu Jiang ,  Fatoumata Camara

IPC分类号： C07D489/08 ,  A61K31/485 ,  A61K47/54

摘要： Abuse-resistant opioid compounds, drug delivery systems, pharmaceutical compositions comprising an opioid covalently bound to a chemical moiety are provided. Methods of delivering an active ingredient to a subject and methods of preventing opioid abuse are also provided.

公开(公告)号：US20170151232A1

公开(公告)日：2017-06-01

申请号：US15431624

申请日：2017-02-13

申请人： John K. Thottathil ,  Albany Molecular Research, Inc.

发明人： Matthew Surman ,  Kathryn Golden ,  Paolo Pasetto ,  Xiaomin Jin ,  Xiaowu Jiang ,  Fatoumata Camara ,  John K. Thottathil

IPC分类号： A61K31/485 ,  C07D489/08

CPC分类号： A61K31/485 ,  A61K47/542 ,  C07D489/08

摘要： Abuse-resistant opioid compounds, drug delivery systems, pharmaceutical compositions comprising an opioid covalently bound to a chemical moiety are provided. Methods of delivering an active ingredient to a subject and methods of preventing opioid abuse are also provided.