公开(公告)号：US06172245B2

公开(公告)日：2001-01-09

申请号：US09465100

申请日：1999-12-16

申请人： John Robert Monnier ,  Jerome Leonard Stavinoha, Jr. ,  Gary Wayne Hartley ,  Emily Elizabeth Jameson ,  Scott Donald Barnicki

发明人： John Robert Monnier ,  Jerome Leonard Stavinoha, Jr. ,  Gary Wayne Hartley ,  Emily Elizabeth Jameson ,  Scott Donald Barnicki

IPC分类号： C07D30110

CPC分类号： C07D303/04 ,  C07D301/10

摘要： Disclosed herein is an improved gas phase process for the selective epoxidation of non-allylic olefins wherein the epoxidation is carried out in the presence of one or more volatile, nitrogen-containing, basic compounds. The presence of a nitrogen-containing basic compound in the olefin-containing reaction gas or vapor suppresses the formation of an organic resinous material which coats the catalyst, thereby decreasing catalyst activity and life and also increases substantially the activity of the epoxidation catalyst. The disclosed process is particularly useful for the continuous manufacture of 3,4-epoxy-1-butene from 1,3-butadiene.

摘要翻译： 本文公开了用于非烯丙烯选择性环氧化的改进的气相方法，其中环氧化在一种或多种挥发性含氮碱性化合物的存在下进行。 含烯烃反应气体或蒸气中含氮碱性化合物的存在抑制了涂覆催化剂的有机树脂材料的形成，从而降低催化剂活性和寿命，并且还显着提高了环氧化催化剂的活性。 所公开的方法对于从1,3-丁二烯连续制备3,4-环氧-1-丁烯是特别有用的。