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1.发明授权High viscosity liquid controlled delivery system and medical or surgical device 失效高粘度液体控制输送系统和医疗或手术装置公开(公告)号：US07833543B2
公开(公告)日：2010-11-16
申请号：US10316441
申请日：2002-12-10
IPC分类号： A01N25/08
CPC分类号： A61K47/10 , A61K8/60 , A61K9/0014 , A61K9/0019 , A61K9/0024 , A61K9/0073 , A61K9/1647 , A61K9/4858 , A61K9/7015 , A61K47/14 , A61K47/26 , A61K47/34 , A61L15/20 , A61L15/44 , A61L24/0015 , A61L24/0026 , A61L26/0066 , A61L27/54 , A61L31/16 , A61L2300/252 , A61L2300/402 , A61L2300/43 , A61L2300/602 , A61Q5/006
摘要： The present invention relates to novel nonpolymeric compounds and compositions that form liquid, high viscosity materials suitable for the delivery of biologically active substances in a controlled fashion, and for use as medical or surgical devices. The materials can optionally be diluted with a solvent to form a material of lower viscosity, rendering the material easy to administer. This solvent may be water insoluble or water soluble, where the water soluble solvent rapidly diffuses or migrates away from the material in vivo, leaving a higher viscosity liquid material.
摘要翻译： 本发明涉及形成液体，高粘度材料的新型非聚合物和组合物，其适于以受控的方式递送生物活性物质，并用作医疗或手术装置。 该材料可任选地用溶剂稀释以形成较低粘度的材料，使得该材料易于施用。 该溶剂可以是水不溶性或水溶性的，其中水溶性溶剂在体内快速扩散或迁移离开材料，留下较高粘度的液体材料。
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公开(公告)号：US20080152708A1
公开(公告)日：2008-06-26
申请号：US11888621
申请日：2007-07-31
CPC分类号： A61K47/10 , A61K8/60 , A61K9/0014 , A61K9/0019 , A61K9/0024 , A61K9/0073 , A61K9/1647 , A61K9/4858 , A61K9/7015 , A61K47/14 , A61K47/26 , A61K47/34 , A61L15/20 , A61L15/44 , A61L24/0015 , A61L24/0026 , A61L26/0066 , A61L27/54 , A61L31/16 , A61L2300/252 , A61L2300/402 , A61L2300/43 , A61L2300/602 , A61Q5/006
摘要： The present invention relates to novel nonpolymeric compounds and compositions that form liquid, high viscosity materials suitable for the delivery of biologically active substances in a controlled fashion, and for use as medical or surgical devices. The materials can optionally be diluted with a solvent to form a material of lower viscosity, rendering the material easy to administer. This solvent may be water insoluble or water soluble, where the water soluble solvent rapidly diffuses or migrates away from the material in vivo, leaving a higher viscosity liquid material.
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3.发明申请High viscosity liquid controlled delivery system and medical or surgical device 审中-公开高粘度液体控制输送系统和医疗或手术装置公开(公告)号：US20080145419A1
公开(公告)日：2008-06-19
申请号：US11888638
申请日：2007-07-31
IPC分类号： A61K9/48 , A61K47/26 , A61K38/02 , A61K38/16 , A61K31/715 , A61K31/727 , A61Q11/00 , A61K31/56 , A61K31/7052 , A61K8/30 , A61K9/14
CPC分类号： A61K47/10 , A61K8/60 , A61K9/0014 , A61K9/0019 , A61K9/0024 , A61K9/0073 , A61K9/1647 , A61K9/4858 , A61K9/7015 , A61K47/14 , A61K47/26 , A61K47/34 , A61L15/20 , A61L15/44 , A61L24/0015 , A61L24/0026 , A61L26/0066 , A61L27/54 , A61L31/16 , A61L2300/252 , A61L2300/402 , A61L2300/43 , A61L2300/602 , A61Q5/006
摘要： The present invention relates to novel nonpolymeric compounds and compositions that form liquid, high viscosity materials suitable for the delivery of biologically active substances in a controlled fashion, and for use as medical or surgical devices. The materials can optionally be diluted with a solvent to form a material of lower viscosity, rendering the material easy to administer. This solvent may be water insoluble or water soluble, where the water soluble solvent rapidly diffuses or migrates away from the material in vivo, leaving a higher viscosity liquid material.
摘要翻译： 本发明涉及形成液体，高粘度材料的新型非聚合物和组合物，其适于以受控的方式递送生物活性物质，并用作医疗或手术装置。 该材料可任选地用溶剂稀释以形成较低粘度的材料，使得该材料易于施用。 该溶剂可以是水不溶性或水溶性的，其中水溶性溶剂在体内快速扩散或迁移离开材料，留下较高粘度的液体材料。
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