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公开(公告)号：US20110124584A1
公开(公告)日：2011-05-26
申请号：US12925357
申请日：2010-10-20
申请人： Jonathan B. Rothbard , Paul L. McGrane , Edgar G. Engleman , C. Garrison Fathman , Erik Kreider
发明人： Jonathan B. Rothbard , Paul L. McGrane , Edgar G. Engleman , C. Garrison Fathman , Erik Kreider
CPC分类号： A61K38/08 , A61K31/137 , A61K31/4178 , A61K31/5377 , A61K38/04
摘要： This invention relates to compositions and methods for treatment of vascular conditions. The invention provides arginine polymers and arginine homopolymers for the treatment and/or prevention of glaucoma, pulmonary hypertension, asthma, chronic obstructive pulmonary disease, erectile dysfunction, Raynaud's syndrome, heparin overdose, vulvodynia, and wound healing. The invention also provides arginine polymers and arginine homopolymers for use in organ perfusate and preservation solutions.
摘要翻译： 本发明涉及用于治疗血管病症的组合物和方法。 本发明提供精氨酸聚合物和精氨酸均聚物，用于治疗和/或预防青光眼，肺动脉高压，哮喘，慢性阻塞性肺病，勃起功能障碍，雷诺综合征，肝素过量，外阴和伤口愈合。 本发明还提供用于器官灌注液和保存溶液的精氨酸聚合物和精氨酸均聚物。
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公开(公告)号：US07820626B2
公开(公告)日：2010-10-26
申请号：US12258265
申请日：2008-10-24
申请人： Jonathan B. Rothbard , Paul L. McGrane , Edgar G. Engleman , C. Garrison Fathman , Erik Kreider
发明人： Jonathan B. Rothbard , Paul L. McGrane , Edgar G. Engleman , C. Garrison Fathman , Erik Kreider
CPC分类号： A61K38/08 , A61K31/137 , A61K31/4178 , A61K31/5377 , A61K38/04
摘要： This invention relates to compositions and methods for treatment of vascular conditions. The invention provides arginine polymers and arginine homopolymers for the treatment and/or prevention of glaucoma, pulmonary hypertension, asthma, chronic obstructive pulmonary disease, erectile dysfunction, Raynaud's syndrome, heparin overdose, vulvodynia, and wound healing. The invention also provides arginine polymers and arginine homopolymers for use in organ perfusate and preservation solutions.
摘要翻译： 本发明涉及用于治疗血管病症的组合物和方法。 本发明提供精氨酸聚合物和精氨酸均聚物，用于治疗和/或预防青光眼，肺动脉高压，哮喘，慢性阻塞性肺病，勃起功能障碍，雷诺综合征，肝素过量，外阴和伤口愈合。 本发明还提供用于器官灌注液和保存溶液的精氨酸聚合物和精氨酸均聚物。
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公开(公告)号：US07557087B2
公开(公告)日：2009-07-07
申请号：US11736689
申请日：2007-04-18
申请人： Jonathan B. Rothbard , Paul L. McGrane , Edgar G. Engleman , C. Garrison Fathman , Erik Kreider
发明人： Jonathan B. Rothbard , Paul L. McGrane , Edgar G. Engleman , C. Garrison Fathman , Erik Kreider
IPC分类号： A61K38/08
CPC分类号： A61K38/08 , A61K31/137 , A61K31/4178 , A61K31/5377 , A61K38/04
摘要： This invention relates to compositions and methods for treatment of vascular conditions. The invention provides arginine polymers and arginine homopolymers for the treatment and/or prevention of glaucoma, pulmonary hypertension, asthma, chronic obstructive pulmonary disease, erectile dysfunction, Raynaud's syndrome, heparin overdose, vulvodynia, and wound healing. The invention also provides arginine polymers and arginine homopolymers for use in organ perfusate and preservation solutions.
摘要翻译： 本发明涉及用于治疗血管病症的组合物和方法。 本发明提供精氨酸聚合物和精氨酸均聚物，用于治疗和/或预防青光眼，肺动脉高压，哮喘，慢性阻塞性肺病，勃起功能障碍，雷诺综合征，肝素过量，外阴和伤口愈合。 本发明还提供用于器官灌注液和保存溶液的精氨酸聚合物和精氨酸均聚物。
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公开(公告)号：US08629115B2
公开(公告)日：2014-01-14
申请号：US12925357
申请日：2010-10-20
申请人： Jonathan B. Rothbard , Paul L. McGrane , Edgar G. Engleman , C. Garrison Fathman , Erik Kreider
发明人： Jonathan B. Rothbard , Paul L. McGrane , Edgar G. Engleman , C. Garrison Fathman , Erik Kreider
CPC分类号： A61K38/08 , A61K31/137 , A61K31/4178 , A61K31/5377 , A61K38/04
摘要： This invention relates to compositions and methods for treatment of vascular conditions. The invention provides arginine polymers and arginine homopolymers for the treatment and/or prevention of glaucoma, pulmonary hypertension, asthma, chronic obstructive pulmonary disease, erectile dysfunction, Raynaud's syndrome, heparin overdose, vulvodynia, and wound healing. The invention also provides arginine polymers and arginine homopolymers for use in organ perfusate and preservation solutions.
摘要翻译： 本发明涉及用于治疗血管病症的组合物和方法。 本发明提供精氨酸聚合物和精氨酸均聚物，用于治疗和/或预防青光眼，肺动脉高压，哮喘，慢性阻塞性肺病，勃起功能障碍，雷诺综合征，肝素过量，外阴和伤口愈合。 本发明还提供用于器官灌注液和保存溶液的精氨酸聚合物和精氨酸均聚物。
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公开(公告)号：US20090053283A1
公开(公告)日：2009-02-26
申请号：US12258265
申请日：2008-10-24
申请人： Jonathan B. Rothbard , Paul L. McGrane , Edgar G. Engleman , C. Garrison Fathman , Erik Kreider
发明人： Jonathan B. Rothbard , Paul L. McGrane , Edgar G. Engleman , C. Garrison Fathman , Erik Kreider
CPC分类号： A61K38/08 , A61K31/137 , A61K31/4178 , A61K31/5377 , A61K38/04
摘要： This invention relates to compositions and methods for treatment of vascular conditions. The invention provides arginine polymers and arginine homopolymers for the treatment and/or prevention of glaucoma, pulmonary hypertension, asthma, chronic obstructive pulmonary disease, erectile dysfunction, Raynaud's syndrome, heparin overdose, vulvodynia, and wound healing. The invention also provides arginine polymers and arginine homopolymers for use in organ perfusate and preservation solutions.
摘要翻译： 本发明涉及用于治疗血管病症的组合物和方法。 本发明提供精氨酸聚合物和精氨酸均聚物，用于治疗和/或预防青光眼，肺动脉高压，哮喘，慢性阻塞性肺病，勃起功能障碍，雷诺综合征，肝素过量，外阴和伤口愈合。 本发明还提供用于器官灌注液和保存溶液的精氨酸聚合物和精氨酸均聚物。
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