公开(公告)号：US08448457B2

公开(公告)日：2013-05-28

申请号：US12624031

申请日：2009-11-23

申请人： Jonathan Cutting ,  Isabelle Gay ,  Oscar Werner Reif

发明人： Jonathan Cutting ,  Isabelle Gay ,  Oscar Werner Reif

IPC分类号： F25C1/00

CPC分类号： F25D17/02 ,  A01N1/0252 ,  F25D2400/02 ,  F25D2600/04

摘要： A system for use in freezing, thawing, transporting or storing biopharmaceutical materials which includes a container, a holder and plurality of heat transfer members. The container is configured to hold biopharmaceutical materials therein. The holder has a cavity for receiving the container and includes an interior surface bounding the cavity. A plurality of pockets contact outer surfaces of the container and is received in the cavity. Each pocket of the plurality of pockets includes a pocket cavity. A heat transfer member actively controls the temperature of biopharmaceutical materials held in the container and is received in the pocket cavity.

摘要翻译： 一种用于冷冻，解冻，运输或储存生物药物材料的系统，其包括容器，保持器和多个传热构件。 容器构造成在其中容纳生物药物材料。 保持器具有用于容纳容器的空腔，并且包括限定空腔的内表面。 多个凹穴接触容器的外表面并被容纳在空腔中。 多个口袋中的每个口袋都包括袋腔。 传热构件主动地控制容纳在容器中的生物药物的温度并被容纳在口腔中。

公开(公告)号：US08371132B2

公开(公告)日：2013-02-12

申请号：US12726513

申请日：2010-03-18

申请人： Jonathan Cutting ,  Isabelle Gay ,  Oscar Werner Reif

发明人： Jonathan Cutting ,  Isabelle Gay ,  Oscar Werner Reif

IPC分类号： F25C1/00

CPC分类号： A61J1/165 ,  A01N1/0252 ,  A01N1/0257 ,  A01N1/0273 ,  B01F5/10 ,  B01F11/0008 ,  B01F11/0082 ,  B01F15/0074 ,  B01F15/065 ,  B01F2015/061 ,  B65D81/3825

摘要： A system for use in freezing, thawing, transporting or storing biopharmaceutical materials which includes a container, a holder and plurality of heat transfer members. The container is configured to hold biopharmaceutical materials therein. The holder has a cavity for receiving the container and includes an interior surface bounding the cavity. A plurality of pockets contact outer surfaces of the container and is received in the cavity. Each pocket of the plurality of pockets includes a pocket cavity. A heat transfer member actively controls the temperature of biopharmaceutical materials held in the container and is received in the pocket cavity.

公开(公告)号：US08651327B2

公开(公告)日：2014-02-18

申请号：US13024085

申请日：2011-02-09

申请人： Jonathan Cutting ,  Oscar Werner Reif

发明人： Jonathan Cutting ,  Oscar Werner Reif

IPC分类号： B67D7/78

CPC分类号： B01L3/52 ,  B01L3/523

摘要： A system for storing biopharmaceutical materials includes a plurality of flexible walls bounding an interior for holding biopharmaceutical materials therein. At least one port is connected to a first wall of the walls and provides fluid communication between the interior and an exterior to allow a draining of the interior. A collapsible conduit includes a plurality of perforations along the conduit. The plurality of perforations is configured to allow flow of the biopharmaceutical materials from the exterior to the interior of the conduit. The conduit has a cross-sectional area transverse to a length of the conduit and the conduit extends from one of the at least one port toward an opposite end of the interior. The conduit is collapsible by the flexible walls and forms a reduced cross-sectional area to allow a flow of the biopharmaceutical materials through and/or along the conduit to the port.

摘要翻译： 用于储存生物药物材料的系统包括围绕内部的多个柔性壁，用于在其中保持生物药物材料。 至少一个端口连接到壁的第一壁并且在内部和外部之间提供流体连通以允许内部的排水。 可折叠导管包括沿导管的多个穿孔。 多个穿孔被配置为允许生物药物材料从外部流到导管的内部。 导管具有横向于管道的长度的横截面面积，并且导管从至少一个端口中的一个朝向内部的相对端延伸。 导管可由柔性壁折叠并形成减小的横截面面积，以允许生物药物材料通过和/或沿管道流到端口。