公开(公告)号：US20240307876A1

公开(公告)日：2024-09-19

申请号：US18674548

申请日：2024-05-24

Applicant: STMICROELECTRONICS S.r.l.

Inventor： Marco CEREDA ,  Lillo RAIA ,  Danilo PIROLA

IPC: B01L3/00 ,  A61B5/15 ,  A61B5/154 ,  B01F33/30 ,  B01F33/40 ,  B01F33/452 ,  B01L9/00 ,  C12M3/06 ,  C12Q1/6806 ,  C12Q1/6844

CPC classification number: B01L3/502753 ,  A61B5/15003 ,  A61B5/150221 ,  A61B5/150351 ,  A61B5/154 ,  B01F33/30 ,  B01F33/406 ,  B01F33/452 ,  B01L3/502715 ,  B01L3/502723 ,  B01L3/50273 ,  B01L3/502738 ,  B01L3/5029 ,  B01L3/508 ,  B01L3/5082 ,  B01L3/52 ,  B01L3/527 ,  B01L9/527 ,  C12M23/16 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150732 ,  B01L3/5023 ,  B01L3/502707 ,  B01L3/50825 ,  B01L3/523 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2200/0621 ,  B01L2200/0642 ,  B01L2200/0668 ,  B01L2200/0673 ,  B01L2200/0689 ,  B01L2200/10 ,  B01L2200/141 ,  B01L2200/16 ,  B01L2300/022 ,  B01L2300/023 ,  B01L2300/044 ,  B01L2300/0609 ,  B01L2300/0681 ,  B01L2300/08 ,  B01L2300/0816 ,  B01L2300/0819 ,  B01L2300/0829 ,  B01L2300/0848 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/0864 ,  B01L2300/087 ,  B01L2300/12 ,  B01L2300/16 ,  B01L2300/1827 ,  B01L2400/04 ,  B01L2400/0406 ,  B01L2400/043 ,  B01L2400/0487 ,  B01L2400/049 ,  B01L2400/0677 ,  C12Q1/6806 ,  C12Q1/6844

Abstract: An analysis unit formed by an analysis body housing an analysis chamber and having a sample inlet and a supply channel configured to fluidically connect the sample inlet to the analysis chamber. Dried assay reagents are arranged in the analysis chamber and are contained in an alveolar mass. For instance, the alveolar mass is a lyophilized mass formed by excipients and by assay-specific reagents.

公开(公告)号：US20240299928A1

公开(公告)日：2024-09-12

申请号：US18412909

申请日：2024-01-15

Applicant: Elemental Scientific, inc.

Inventor： Daniel R. Wiederin ,  Austin Schultz

IPC: B01L3/00 ,  G01N1/38 ,  G01N21/71 ,  G01N21/73 ,  G01N35/10 ,  H01J49/04 ,  H01J49/10

CPC classification number: B01L3/502 ,  B01L3/523 ,  B01L3/567 ,  G01N1/38 ,  G01N21/73 ,  G01N35/1097 ,  H01J49/0431 ,  B01L2200/0605 ,  B01L2300/024 ,  B01L2300/049 ,  B01L2300/0806 ,  B01L2300/0861 ,  B01L2300/0867 ,  B01L2400/0487 ,  B01L2400/049 ,  B01L2400/06 ,  G01N2001/386 ,  G01N21/71 ,  G01N2035/1032 ,  H01J49/105

Abstract: Sample preparation systems and methods are described having pump control, valve configurations, and control logic that facilitate automatic, inline preparation dilutions of a sample according to at least two dilution operating modes. A system embodiment includes, but is not limited to a first pump configured to drive a carrier fluid; a second pump configured to drive a diluent; and a plurality of selection valves fluidically coupled with the first pump and the second pump, the plurality of selection valves being configured to direct fluid flows from the first pump and the second pump according to at least two modes of operation to provide a single-stage sample dilution according to a first operating mode and to provide a dual-stage sample dilution according to a second operating mode.

公开(公告)号：US20240278246A1

公开(公告)日：2024-08-22

申请号：US18681121

申请日：2022-07-28

Applicant: Creganna Unlimited Company

Inventor： Luis FERNANDEZ LEDESMA ,  Andreu LLOBERA ADAN ,  Irene VARELA LENIZ ,  Pablo GARCÍA DE MADINABEITIA MERINO

IPC: B01L3/00

CPC classification number: B01L3/523 ,  B01L3/502715 ,  B01L2200/027 ,  B01L2200/16 ,  B01L2300/0672 ,  B01L2400/0478 ,  B01L2400/0481

Abstract: This invention relates to a blister opening system comprising a blister body (1) arranged over a support surface (1′″); a header (2) comprising an impelling surface (2′), wherein said header (2) is movable relative to the blister body (1) and transmits a pressure against the blister body (1) through the impelling surface (2′) in a pushing direction (3); and a fluidic outlet channel (4) fluidically connected to the blister body (1). The system is characterized in that the impelling surface (2′) is arranged such that, in a relative position between the header (2) and the blister body (1) the pushing direction (3) and the support surface (1′″) form a relative angle (5) substantially different from 90°. The pressure of the impelling surface (2′) against the blister body (1) configures a gas entrapment volume (1″) at an opposite side of the blister body (1) with regard to the fluidic outlet channel (4).

公开(公告)号：US20240264189A1

公开(公告)日：2024-08-08

申请号：US18436718

申请日：2024-02-08

Applicant: Abbott Laboratories

Inventor： Roger W. Accurso

IPC: G01N35/10 ,  B01L3/00 ,  G01N1/28

CPC classification number: G01N35/1002 ,  B01L3/523 ,  B01L13/02 ,  G01N1/28 ,  G01N35/1079 ,  B01L2200/025 ,  B01L2200/04 ,  B01L2300/042 ,  B01L2300/049 ,  B01L2300/0672 ,  G01N2035/1025

Abstract: Cradles for draining liquid from containers are described herein. An example apparatus includes a housing having a bottom wall, a side wall and an open top. The housing is to receive a container having liquid. The example apparatus includes a probe extending upward from the bottom wall toward the open top and is to drain the liquid from the container when the probe is inserted into the container. The example apparatus also includes a sliding lock slidably disposed within the housing that receives a cap or top of the container when the container is inserted into the housing. The sliding lock includes a key slot. The sliding lock is movable when a cap or top of the container has a matching key that engages the key slot, which enables the sliding lock to move downward to expose the probe and drain the liquid from the container.

公开(公告)号：US12053781B2

公开(公告)日：2024-08-06

申请号：US18459997

申请日：2023-09-01

Applicant: Waters Technologies Corporation

Inventor： Sean Eric Anderson

IPC: C12N15/10 ,  A61K45/06 ,  B01L3/00 ,  B01L3/02 ,  G01N21/35 ,  G01N21/3504 ,  G01N21/64 ,  G01N33/00 ,  G01N33/50 ,  G01N33/53 ,  G01N33/543 ,  G01N33/574

CPC classification number: B01L3/523 ,  B01L2300/048 ,  B01L2300/0663 ,  B01L2300/14 ,  B01L2400/0487 ,  B01L2400/082

Abstract: Disclosed herein are solvent reservoir systems for steady flow delivery and simultaneous monitoring of solvent level and solvent density within the solvent reservoir systems and methods for monitoring the solvent reservoir systems and providing feedback to a user or adjusting the systems in response to the monitored characteristics.

公开(公告)号：US20240198326A1

公开(公告)日：2024-06-20

申请号：US18592190

申请日：2024-02-29

Applicant: WATTS REGULATOR CO.

Inventor： Dorian Cauceglia

IPC: B01L3/00 ,  B01D15/36 ,  G01N21/78 ,  G01N33/18

CPC classification number: B01L3/502 ,  B01D15/363 ,  B01L3/523 ,  B01L3/567 ,  G01N21/78 ,  G01N33/18 ,  B01L2200/16 ,  B01L2300/069 ,  B01L2300/12 ,  B01L2400/0605

Abstract: Stabilized indicator compositions, and systems and methods using the same are described. In embodiments the stabilized indicator compositions include a solvent, an indicator, a stabilizer for the indicator, and optionally a buffer. In embodiments the indicator is or includes N,N-diethyl-p-phenylene diamine (DPD). Systems and methods utilizing the stabilized indicator composition to determine an amount of at least one constituent in a test sample (e.g., water) are also described. In embodiments, the systems and methods remove the stabilizer from the stabilized indicator composition to produce a fluid flow containing un stabilized indicator, which is then combined with a fluid from a sample source to form a test sample for analysis.

公开(公告)号：US11952618B2

公开(公告)日：2024-04-09

申请号：US17144708

申请日：2021-01-08

Applicant: ROCHE MOLECULAR SYSTEMS, INC.

Inventor： Jon Faiz Kayyem ,  Jayashankar Srinivasan ,  Sean Ford

IPC: B01L3/00 ,  C12Q1/6825 ,  B01L7/00 ,  B01L9/00

CPC classification number: C12Q1/6825 ,  B01L3/502715 ,  B01L3/502738 ,  B01L3/502784 ,  B01L3/523 ,  B01L7/52 ,  B01L9/527 ,  B01L2200/025 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/021 ,  B01L2300/0672 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/1822 ,  B01L2300/1827 ,  B01L2400/0427 ,  B01L2400/0481 ,  B01L2400/0683

Abstract: This invention provides biochip cartridges and instrument devices for the detection and/or analysis of target analytes from patient samples.

公开(公告)号：US11906535B2

公开(公告)日：2024-02-20

申请号：US18065079

申请日：2022-12-13

Applicant: Ventana Medical Systems, Inc.

Inventor： Isabel Barbero-Ortega ,  Philip Roper ,  Shane Rowland

IPC: G01N35/10 ,  B01L3/02 ,  B01L3/00

CPC classification number: G01N35/1002 ,  B01L3/0293 ,  B01L3/523 ,  G01N35/10 ,  B01L2400/0611 ,  B01L2400/0616 ,  G01N2035/102 ,  G01N2035/1006

Abstract: The present disclosure is directed to methods and devices for reducing or otherwise mitigating accumulated reagent material and/or fluids within a dispense nozzle of a dispenser.

公开(公告)号：US20240042449A1

公开(公告)日：2024-02-08

申请号：US18382747

申请日：2023-10-23

Applicant: Solios Diagnostics GmbH

Inventor： Dieter Hassberg

IPC: B01L3/00

CPC classification number: B01L3/523 ,  B01L2300/042 ,  B01L2300/069 ,  B01L2300/0832

Abstract: The present invention relates to a test device and a test method for carrying out a test directed to the detection of an organic structure. The test device comprises a housing wherein a receiving area for receiving a sample collection stick, a liquid reservoir forming a separated area within the housing and filled with a reaction solution, and an analysis area are received. Preferably, the reaction solution is received in a cartridge sealed at both ends by a separation layer.

公开(公告)号：US20230372942A1

公开(公告)日：2023-11-23

申请号：US18198508

申请日：2023-05-17

Applicant: STRATEC SE

Inventor： Waldemar Lukhaub ,  Martin Trump ,  Sara Zimmermann

IPC: B01L3/00

CPC classification number: B01L3/523 ,  B01L2300/042 ,  B01L2300/0848

Abstract: A sealing for a reagent container and provides a sealing plug which can be adapted to the respective reagent container. Within the meaning of the present disclosure the terms plug, and stopper will be used synonymously. A liquid which is deposited in a reagent container like a vial or tube is protected by a plug from both, evaporation, and oxidation by ambient air during its presence in the reagent container. In addition, when the reagent container is provided to the analyser, the plug reduces evaporation and oxidation of liquids like reagents. A system comprising the plug and a method for using the plug are also disclosed.