公开(公告)号：US20120065102A1

公开(公告)日：2012-03-15

申请号：US13298433

申请日：2011-11-17

申请人： Jonathan WEST ,  Jean-Philippe FRIMAT ,  Julia SISNAISKE ,  Jan HENGSTLER ,  Christoph VAN THRIEL

发明人： Jonathan WEST ,  Jean-Philippe FRIMAT ,  Julia SISNAISKE ,  Jan HENGSTLER ,  Christoph VAN THRIEL

IPC分类号： C40B30/06

CPC分类号： G01N33/5058 ,  G01N33/5032

摘要： A method for the analysis of neurite growth is described, in which a substrate having an array pattern is provided, which has first regions on which neurons and cells similar to neurons can adhere, whereby the first regions are surrounded by second regions, in each instance, on which neurons and cells similar to neurons cannot adhere, whereby neurons or cells similar to neurons adhere only on the first regions of the array, and subsequently, the neurons or cells similar to neurons are exposed to one or multiple or no treatment(s), and during this/these treatment(s) and/or afterwards, the neurite outgrowths from the neurons or cells similar to neurons are analyzed by recognizing and quantifying the connections that are formed between the first regions by means of the neurite outgrowths.

摘要翻译： 描述了用于分析神经突生长的方法，其中提供了具有阵列图案的基底，其具有第一区域，神经元和细胞类似于神经元可附着在其上，由此第一区域被第二区域包围 ，其中与神经元相似的神经元和细胞不能粘附，由此与神经元相似的神经元或细胞仅粘附在阵列的第一区域上，随后，与神经元相似的神经元或细胞暴露于一种或多种或不进行治疗 ），并且在该/这些处理期间和/或之后，通过识别和量化通过神经突生长在第一区域之间形成的连接来分析与神经元相似的神经元或细胞的神经突向外生长。

公开(公告)号：US20130266936A1

公开(公告)日：2013-10-10

申请号：US13721374

申请日：2012-12-20

申请人： Eric STEINER ,  Jan HENGSTLER ,  Jens Sagemüller

发明人： Eric STEINER ,  Jan HENGSTLER ,  Jens Sagemüller

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118

摘要： The invention relates to the diagnosis, prognosis, monitoring, and treatment of neoplastic diseases such as tumor diseases, especially tumor diseases of the endometrium and the metastases thereof.

摘要翻译： 本发明涉及肿瘤疾病，特别是子宫内膜的肿瘤疾病及其转移的肿瘤疾病的诊断，预后，监测和治疗。