公开(公告)号：US08785416B2

公开(公告)日：2014-07-22

申请号：US13520069

申请日：2010-12-22

申请人： Josep Verges Milano ,  Antonio Garcia Garcia ,  Ramon Ruhi Roura ,  Eulalia Montell Bonaventura ,  Manuela Garcia Lopez ,  Carlos Raul Alaez Verson ,  Josep Escaich Ferrer ,  Javier Egea Maiquez ,  Pilar Negredo Madrigal ,  Silvia Lorrio Gonzalez

发明人： Josep Verges Milano ,  Antonio Garcia Garcia ,  Ramon Ruhi Roura ,  Eulalia Montell Bonaventura ,  Manuela Garcia Lopez ,  Carlos Raul Alaez Verson ,  Josep Escaich Ferrer ,  Javier Egea Maiquez ,  Pilar Negredo Madrigal ,  Silvia Lorrio Gonzalez

IPC分类号： A61K31/7016 ,  A61K31/715 ,  C07H3/04 ,  C07H5/06

CPC分类号： A61K31/7016

摘要： The present invention relates to the use of a series of sulphated disaccharides for the preparation of a medicament for the treatment or prevention of a neurodegenerative and/or neurovascular disease, of a traumatic brain injury or of a traumatic spinal cord injury. The present invention also relates to the use of said sulphated disaccharides for the preparation of a neuroprotective medicament or of an antioxidant medicament. The neurodegenerative and/or neurovascular diseases are preferably: Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis and stroke.

摘要翻译： 本发明涉及一系列硫酸化二糖在制备用于治疗或预防神经变性和/或神经血管疾病，创伤性脑损伤或创伤性脊髓损伤的药物中的用途。 本发明还涉及所述硫酸化二糖用于制备神经保护药物或抗氧化剂药物的用途。 神经变性和/或神经血管疾病优选为：阿尔茨海默氏病，帕金森病，肌萎缩性侧索硬化和中风。

公开(公告)号：US20120309707A1

公开(公告)日：2012-12-06

申请号：US13520069

申请日：2010-12-22

申请人： Josep Verges Milano ,  Antonio Garcia Garcia ,  Ramon Ruhi Roura ,  Eulalia Montell Bonaventura ,  Manuela Garcia Lopez ,  Carlos Raul Alaez Verson ,  Josep Escaich Ferrer ,  Javier Egea Maiquez ,  Pilar Negredo Madrigal ,  Silvia Lorrio Gonzalez

发明人： Josep Verges Milano ,  Antonio Garcia Garcia ,  Ramon Ruhi Roura ,  Eulalia Montell Bonaventura ,  Manuela Garcia Lopez ,  Carlos Raul Alaez Verson ,  Josep Escaich Ferrer ,  Javier Egea Maiquez ,  Pilar Negredo Madrigal ,  Silvia Lorrio Gonzalez

IPC分类号： A61K31/7016 ,  A61P25/16 ,  C07H5/04 ,  A61P25/28 ,  A61P25/00

CPC分类号： A61K31/7016

摘要： The present invention relates to the use of a series of sulphated disaccharides for the preparation of a medicament for the treatment or prevention of a neurodegenerative and/or neurovascular disease, of a traumatic brain injury or of a traumatic spinal cord injury. The present invention also relates to the use of said sulphated disaccharides for the preparation of a neuroprotective medicament or of an antioxidant medicament. The neurodegenerative and/or neurovascular diseases are preferably: Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis and stroke.

摘要翻译： 本发明涉及一系列硫酸化二糖在制备用于治疗或预防神经变性和/或神经血管疾病，创伤性脑损伤或创伤性脊髓损伤的药物中的用途。 本发明还涉及所述硫酸化二糖用于制备神经保护药物或抗氧化剂药物的用途。 神经变性和/或神经血管疾病优选为：阿尔茨海默氏病，帕金森病，肌萎缩性侧索硬化和中风。