公开(公告)号：US6159159A

公开(公告)日：2000-12-12

申请号：US224182

申请日：1998-12-31

申请人： Joseph M. Canter ,  Yongwu Yang ,  Wanglong Zhou ,  Victor S. Sapirstein ,  Melvin P. Ehrlich ,  James S. Harrison ,  Eugene Katsman ,  Omanand Koul ,  Michael Y. Lu ,  Michael A. Greenwald

发明人： Joseph M. Canter ,  Yongwu Yang ,  Wanglong Zhou ,  Victor S. Sapirstein ,  Melvin P. Ehrlich ,  James S. Harrison ,  Eugene Katsman ,  Omanand Koul ,  Michael Y. Lu ,  Michael A. Greenwald

IPC分类号： A61B10/00

CPC分类号： A61B10/0012 ,  A61B2010/0025 ,  Y10S436/906

摘要： A quantitative process for monitoring female fertility cycle wherein the process involves directing a laser beam, preferably generated by a diode laser, onto an area of a slide containing an air-dried sample of a female body fluid. The diffraction pattern resulting from the sample is detected by a two-dimensional photo diode array and analyzed by a microprocessor. If a ferning pattern exists, such pattern will generate a characteristic structure in the diffraction pattern which is then detected by the photo diode array. If no ferning occurs, the corresponding diffraction pattern will be structureless. The microprocessor is programmed with an algorithm to produce a quantitative index of ferning indicating quantitatively the ferning level. Preferably, a plurality of spots on the sample are measured to determine the ferning level at each spot, and the microprocessor then makes a final determination as to final ferning level on the basis of the test results of all of the spots. This significantly increases the reliability of the final test result, since a defect at one test spot or anomaly of one test result will not be fatal to the final result.

摘要翻译： 一种用于监测雌性生育周期的定量过程，其中该方法包括将优选由二极管激光产生的激光束引导到含有女性体液的空气干燥样品的载玻片的区域上。 由样品产生的衍射图由二维光电二极管阵列检测并由微处理器分析。 如果存在镀层图案，则这种图案将产生衍射图案中的特征结构，然后由光电二极管阵列检测。 如果没有发生发光，相应的衍射图将是无结构的。 微处理器用一种算法进行编程，以产生定量指定的定量指标。 优选地，测量样品上的多个点以确定每个点处的熨烫水平，然后微处理器基于所有点的测试结果对最终熨烫水平进行最终确定。 这显着增加了最终测试结果的可靠性，因为一个测试点的缺陷或一个测试结果的异常对最终结果不会是致命的。