TRAF family proteins
    1.
    发明授权
    TRAF family proteins 失效
    TRAF家族蛋白

    公开(公告)号:US07208581B1

    公开(公告)日:2007-04-24

    申请号:US09706325

    申请日:2000-11-03

    IPC分类号: C07K16/00 C12P21/08 C12N5/06

    CPC分类号: C07K16/18

    摘要: In accordance with the present invention, there are provided novel TRAF-Protein-Binding-Domain polypeptides (TPBDs). The invention also provides nucleic acid molecules encoding TPBDs, vectors containing these nucleic acid molecules and host cells containing the vectors. The invention also provides antibodies that can specifically bind to invention TPBDs. Such TPBDs and/or anti-TPBD antibodies are useful for discovery of drugs that suppress autoimmunity, inflammation, allergy, allograph rejection, sepsis, and other diseases.

    摘要翻译: 根据本发明,提供了新型TRAF-蛋白结合域多肽(TPBD)。 本发明还提供编码TPBD的核酸分子,含有这些核酸分子的载体和含有载体的宿主细胞。 本发明还提供可以特异性结合本发明的TPBD的抗体。 这样的TPBD和/或抗TPBD抗体可用于发现抑制自身免疫,炎症,过敏,同种异体排斥,败血症和其它疾病的药物。

    TRAF family proteins
    2.
    发明授权
    TRAF family proteins 失效
    TRAF家族蛋白

    公开(公告)号:US07666607B1

    公开(公告)日:2010-02-23

    申请号:US11788741

    申请日:2007-04-20

    CPC分类号: C07K16/18

    摘要: In accordance with the present invention, there are provided novel TRAF-Protein-Binding-Domain polypeptides (TPBDs). The invention also provides nucleic acid molecules encoding TPBDs, vectors containing these nucleic acid molecules and host cells containing the vectors. The invention also provides antibodies that can specifically bind to invention TPBDs. Such TPBDs and/or anti-TPBD antibodies are useful for discovery of drugs that suppress autoimmunity, inflammation, allergy, allograph rejection, sepsis, and other diseases.

    摘要翻译: 根据本发明,提供了新型TRAF-蛋白结合域多肽(TPBD)。 本发明还提供编码TPBD的核酸分子,含有这些核酸分子的载体和含有载体的宿主细胞。 本发明还提供可以特异性结合本发明的TPBD的抗体。 这样的TPBD和/或抗TPBD抗体可用于发现抑制自身免疫,炎症,过敏,同种异体排斥,败血症和其它疾病的药物。

    NOVEL TRAF FAMILY PROTEINS
    3.
    发明申请
    NOVEL TRAF FAMILY PROTEINS 审中-公开
    新型TRAF家族蛋白

    公开(公告)号:US20100324267A1

    公开(公告)日:2010-12-23

    申请号:US12642723

    申请日:2009-12-18

    IPC分类号: C07K14/00 C07H21/04

    CPC分类号: C07K16/18

    摘要: In accordance with the present invention, there are provided novel TRAF-Protein-Binding-Domain polypeptides (TPBDs). The invention also provides nucleic acid molecules encoding TPBDs, vectors containing these nucleic acid molecules and host cells containing the vectors. The invention also provides antibodies that can specifically bind to invention TPBDs. Such TPBDs and/or anti-TPBD antibodies are useful for discovery of drugs that suppress autoimmunity, inflammation, allergy, allograph rejection, sepsis, and other diseases.

    摘要翻译: 根据本发明,提供了新型TRAF-蛋白结合域多肽(TPBD)。 本发明还提供编码TPBD的核酸分子,含有这些核酸分子的载体和含有载体的宿主细胞。 本发明还提供可以特异性结合本发明的TPBD的抗体。 这样的TPBD和/或抗TPBD抗体可用于发现抑制自身免疫,炎症,过敏,同种异体排斥,败血症和其它疾病的药物。