专利检索 ap:("Julius-Maximilians-Universitaet Wuerzburg") AND inv:"Andreas HARTUNG" 第 1 页

1.

发明申请
TETRAHYDROISOQUINOLINONE DERIVATIVES AND THEIR USE IN THE INHIBITION OF THE HSP70 PROTEIN 有权

公开(公告)号：US20170152229A1

公开(公告)日：2017-06-01

申请号：US15316279

申请日：2014-06-03

申请人： Julius-Maximilians-Universitaet Wuerzburg

发明人： Manik CHATTERJEE , Andreas HARTUNG , Ulrike HOLZGRABE , Elisabeth MUELLER , Ulrich PEINZ , Christoph SOTRIFFER , David ZILIAN

IPC分类号： C07D217/26 , C07D401/12

CPC分类号： C07D217/26 , C07D401/12

摘要： The present invention relates to tetrahydroisoquinolinone derivatives, a pharmaceutical composition comprising the same and the use of these derivatives in the inhibition of the Hsp70 protein. The compounds are useful in the treatment or inhibition of cancer, autoimmune disease, rheumatoid arthritis, inflammatory bowel disease and psoriasis.