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    PYRIMIDINE NUCLEOSIDE DERIVATIVES, SYNTHESIS METHODS AND USES THEREOF FOR PREPARING ANTI-TUMOR AND ANTI-VIRUS MEDICAMENTS
    1.
    发明申请
    PYRIMIDINE NUCLEOSIDE DERIVATIVES, SYNTHESIS METHODS AND USES THEREOF FOR PREPARING ANTI-TUMOR AND ANTI-VIRUS MEDICAMENTS 有权
    吡咯烷酮核苷衍生物，合成方法及其制备抗肿瘤药物和抗病毒药物的用途

    公开(公告)号：US20130303747A1

    公开(公告)日：2013-11-14

    申请号：US13820993

    申请日：2011-09-02

    申请人： Junbiao Chang ,  Haoyun An ,  Xuejun Yu ,  Xiaohe Guo

    发明人： Junbiao Chang ,  Haoyun An ,  Xuejun Yu ,  Xiaohe Guo

    IPC分类号： C07H19/06

    CPC分类号： C07H19/06 ,  C07H19/14

    摘要： The present invention relates to the field of pharmacochemistry. Disclosed are fluorinated and azido-substituted pyrimidine nucleoside derivatives, and preparation methods and uses thereof. The structural formula is as shown (I). These compounds can be used for preparing medicaments for treating diseases such as tumors and viral infections, and can be used separately or in combination with other medicaments. The compounds also have effective activity against diseases such as tumors and viral infections, while having few side effects, and thus have potential application value.

    摘要翻译： 本发明涉及药物化学领域。 公开了氟化和叠氮基取代的嘧啶核苷衍生物及其制备方法和用途。 结构式如图（I）所示。 这些化合物可用于制备用于治疗诸如肿瘤和病毒感染的疾病的药物，并且可以单独使用或与其它药物组合使用。 该化合物还具有抗肿瘤和病毒感染等疾病的有效活性，同时副作用少，具有潜在的应用价值。

    Pyrimidine nucleoside derivatives, synthesis methods and uses thereof for preparing anti-tumor and anti-virus medicaments
    2.
    发明授权
    Pyrimidine nucleoside derivatives, synthesis methods and uses thereof for preparing anti-tumor and anti-virus medicaments 有权
    嘧啶核苷衍生物，其制备抗肿瘤和抗病毒药物的合成方法和用途

    公开(公告)号：US09422321B2

    公开(公告)日：2016-08-23

    申请号：US13820993

    申请日：2011-09-02

    申请人： Junbiao Chang ,  Haoyun An ,  Xuejun Yu ,  Xiaohe Guo

    发明人： Junbiao Chang ,  Haoyun An ,  Xuejun Yu ,  Xiaohe Guo

    IPC分类号： C07H19/00 ,  C07H19/06 ,  C07H19/14

    CPC分类号： C07H19/06 ,  C07H19/14

    摘要： The present invention relates to the field of pharmacochemistry. Disclosed are fluorinated and azido-substituted pyrimidine nucleoside derivatives, particularly compounds of the formula shown below: Also disclosed are methods of preparation and uses for these compounds. The compounds can be used for preparing medicaments for treating diseases such as tumors and viral infections, and can be used separately or in combination with other medicaments. The compounds also have effective activity against diseases such as tumors and viral infections, while having few side effects, and thus have potential application value.

    摘要翻译： 本发明涉及药物化学领域。 公开了氟化和叠氮基取代的嘧啶核苷衍生物，特别是下列化学式的化合物：还公开了这些化合物的制备方法和用途。 该化合物可用于制备用于治疗疾病如肿瘤和病毒感染的药物，并且可以单独使用或与其它药物组合使用。 该化合物还具有抗肿瘤和病毒感染等疾病的有效活性，同时副作用少，具有潜在的应用价值。