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    Glucuronic acid-containing glucan, process for production of same, and use of same
    2.
    发明授权
    Glucuronic acid-containing glucan, process for production of same, and use of same 有权
    含有葡萄糖醛酸的葡聚糖，其制造方法及其用途

    公开(公告)号：US08575131B2

    公开(公告)日：2013-11-05

    申请号：US13318958

    申请日：2010-05-10

    申请人： Junichi Kadokawa ,  Takeshi Takaha ,  Akiko Kubo ,  Michiyo Yanase ,  Kayo Hosoya

    发明人： Junichi Kadokawa ,  Takeshi Takaha ,  Akiko Kubo ,  Michiyo Yanase ,  Kayo Hosoya

    IPC分类号： A61K31/70 ,  C07H1/00

    CPC分类号： A61K47/36 ,  A61K49/0002 ,  C08B37/0009 ,  C12N9/1051 ,  C12P19/04 ,  C12Y204/01001

    摘要： An object of the present invention is to provide a uronic acid-containing glucan or a modified product thereof. The glucuronic acid-containing glucan of the present invention is a glucuronic acid-containing glucan in which a glucuronic acid residue is bound to at least one non-reducing end of a glucan, and the glucan is a branched α-1,4 glucan or a linear α-1,4 glucan. The glucuronic acid-containing glucan of the present invention can be provided by allowing α-glucan phosphorylase derived from Aquifex aeolicus VF5 to act on glucuronic acid-1-phosphate to thereby transfer a glucuronic acid residue to the non-reducing end of the receptor glucan.

    摘要翻译： 本发明的目的是提供一种含糖醛酸的葡聚糖或其改性产物。 本发明的含葡萄糖醛酸的葡聚糖是葡萄糖醛酸的葡聚糖，其中葡萄糖醛酸残基与葡聚糖的至少一个非还原末端结合，葡聚糖是支链的α-1,4葡聚糖或 线型α-1,4葡聚糖。 本发明的含葡萄糖醛酸的葡聚糖可以通过使来源于水溶性水蛭素VF5的α-葡聚糖磷酸化酶作用于葡糖醛酸-1-磷酸酯上，从而将葡萄糖醛酸残基转移到受体葡聚糖的非还原末端来提供 。