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公开(公告)号:US20160280719A1
公开(公告)日:2016-09-29
申请号:US15037116
申请日:2014-11-20
申请人: Jutta BLANK , Guido BOLD , Vincent BORDAS , Simona COTESTA , Vito GUAGNANO , Heinrich RUEGER , Andrea VAUPEL
发明人: Jutta BLANK , Guido BOLD , Vincent BORDAS , Simona COTESTA , Vito GUAGNANO , Heinrich RUEGER , Andrea VAUPEL
IPC分类号: C07D519/00 , A61K31/437 , A61K31/444 , A61K31/5025 , A61K31/4439 , A61K31/506 , A61K31/513 , C07D487/04 , A61K31/4192
CPC分类号: C07D519/00 , A61K31/4192 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/5025 , A61K31/506 , A61K31/513 , A61P35/00 , C07D487/04
摘要: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.