公开(公告)号：US11376266B2

公开(公告)日：2022-07-05

申请号：US16067906

申请日：2017-01-05

Applicant: KEIO UNIVERSITY ,  TOKYO INSTITUTE OF TECHNOLOGY

Inventor： Hideyuki Saya ,  Osamu Nagano ,  Kenji Tsuchihashi ,  Kentaro Suina ,  Nobuhiro Nishiyama ,  Hiroyasu Takemoto ,  Takahiro Nomoto ,  Makoto Matsui ,  Keishiro Tomoda ,  Naoki Yamada ,  Tsukasa Nishimori

IPC: A61K31/635 ,  A61K47/60 ,  A61K9/00

Abstract: The present invention is directed to provide antitumor agent including water-soluble sulfasalazine as an active ingredient. Antitumor agents were obtained with, as the water-soluble sulfasalazine, a PEG-modified sulfasalazine represented by the following formula: wherein an average value of n is 4 or larger and 1136 or smaller.