公开(公告)号：US09808443B1

公开(公告)日：2017-11-07

申请号：US15362733

申请日：2016-11-28

Applicant: KING SAUD UNIVERSITY

Inventor： Mashooq Ahmad Bhat ,  Mohamed A. Al-Omar ,  Mohammad Raish ,  Mushtaq Ahmad Ansari ,  Hatem A. Abuelizz

IPC: A61K31/404 ,  C07D209/18

CPC classification number: A61K31/404 ,  C07D209/18

Abstract: Cyclooxygenase inhibitors include compounds of the formula: where R represents phenyl, nitrophenyl, 2-nitrophenyl, 3-nitrophenyl, 4-nitrophenyl, 4-chlorophenyl, 2,4-dichlorophenyl, 3,4-dimethoxyphenyl, 2-methoxyphenyl, 4-hydroxyphenyl, dimethylaminophenyl, 3-methoxyphenyl, 4-ethoxyphenyl, 2,4,5-trimethoxyphenyl, 3,4,5-trimethoxyphenyl, 2,4,6-trimethoxyphenyl, and 2,4-dimethoxyphenyl, 3-hydroxyphenyl, 4-dimethylaminophenyl, or 2,3,4-trimethoxyphenyl.