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公开(公告)号：US11576628B2
公开(公告)日：2023-02-14
申请号：US16959289
申请日：2018-12-26
摘要： Emission imaging data are reconstructed to generate a low dose reconstructed image. Standardized uptake value (SUV) conversion (30) is applied to convert the low dose reconstructed image to a low dose SUV image. A neural network (46, 48) is applied to the low dose SUV image to generate an estimated full dose SUV image. Prior to applying the neural network the low dose reconstructed image or the low dose SUV image is filtered using a low pass filter (32). The neural network is trained on a set of training low dose SUV images and corresponding training full dose SUV images to transform the training low dose SUV images to match the corresponding training full dose SUV images, using a loss function having a mean square error loss component (34) and a loss component (36) that penalizes loss of image texture and/or a loss component (38) that promotes edge preservation.
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公开(公告)号：US11175418B2
公开(公告)日：2021-11-16
申请号：US16649416
申请日：2018-09-12
发明人： Chuanyong Bai , Andriy Andreyev , Shushen Lin , Bin Zhang , Michael Allen Miller , Xiyun Song , Jinghan Ye , Shekhar Dwivedi , Zhiqiang Hu , Yu-Lung Hsieh , Ilya Brodskiy , Thomas Christopher Bulgrin , Yang-Ming Zhu , Douglas B. McKnight
摘要： A non-transitory computer-readable medium storing instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform a quality control (QC) method (100). The method includes: receiving a current QC data set acquired by a pixelated detector (14) and one or more prior QC data sets acquired by the pixelated detector; determining stability levels of detector pixels (16) of the pixelated detector over time from the current QC data set and the one or more prior QC data sets; labeling a detector pixel of the pixelated detector as dead when the stability level determined for the detector pixel is outside of a stability threshold range; and displaying, on a display device (24) operatively connected with the workstation, an identification (28) of the detector pixels labelled as dead.
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公开(公告)号：US11798205B2
公开(公告)日：2023-10-24
申请号：US16959219
申请日：2019-01-02
发明人： Chuanyong Bai , Andriy Andreyev , Bin Zhang , James Gurian , Zhiqiang Hu , Yu-Lung Hsieh , Shekhar Dwivedi , Jinghan Ye , Xiyun Song , Michael Allen Miller
CPC分类号： G06T11/006 , G06T5/002 , G06T7/0012 , G06T2200/24 , G06T2207/10081 , G06T2207/30004
摘要： A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100). The method includes: determining a weighting parameter (13) of an edge-preserving regularization or penalty of a regularized image reconstruction of an image acquisition device (12) for an imaging data set obtained by the image acquisition device; determining an edge sensitivity parameter (γ) of the edge-preserving algorithm for the imaging data set obtained by the image acquisition device; and reconstructing the imaging data set obtained by the image acquisition device to generate a reconstructed image by applying the regularized image reconstruction including the edge-preserving regularization or penalty with the determined weighting and edge sensitivity parameters to the imaging data set obtained by the image acquisition device.
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公开(公告)号：US11061151B2
公开(公告)日：2021-07-13
申请号：US16466587
申请日：2017-12-04
发明人： Chuanyong Bai , Andriy Andreyev , Bin Zhang , Zhiqiang Hu
摘要： A positron emission tomography (PET) detector array includes an enclosing radiation detector array (10) comprising radiation detector elements (14, 16) effective for detecting 511 keV radiation emanating from inside the radiation detector array. The radiation detector pixels of the cylindrical radiation detector array include both higher speed radiation detector elements (14) and lower speed radiation detector elements (16). The lower speed radiation detector pixels have a temporal resolution that is coarser than a temporal resolution of the higher speed radiation detector pixels.
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公开(公告)号：US10977841B2
公开(公告)日：2021-04-13
申请号：US16317656
申请日：2017-07-20
摘要： An imaging device (1) includes a positron emission tomography (PET) scanner (10) including radiation detectors (12) and coincidence circuitry for detecting electron-positron annihilation events as 511 keV gamma ray pairs defining lines of response (LORs) with each event having a detection time difference At between the 511 keV gamma rays of the pair. At least one processor (30) is programmed to reconstruct a dataset comprising detected electron-positron annihilation events acquired for a region of interest by the PET scanner to form a reconstructed PET image wherein the reconstruction includes TOF localization of the events along respective LORs using a TOF kernel having a location parameter dependent on At and a TOF kernel width or shape that varies over the region of interest. A display device (34) is configured to display the reconstructed PET image.
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6.发明授权公开(公告)号：US10925554B2
公开(公告)日：2021-02-23
申请号：US15533749
申请日：2015-12-03
发明人： Andriy Andreyev , Manoj Narayanan , Bin Zhang , Zhiqiang Hu , Yu-Lung Hsieh , Xiyun Song , Jinghan Ye
摘要： A radioemission scanner (12) is operated to acquire tomographic radioemission data of a radiopharmaceutical in a subject in an imaging field of view (FOV). An imaging system is operated to acquire extension imaging data of the subject in an extended FOV disposed outside of and adjacent the imaging FOV along an axial direction (18). A distribution of the radiopharmaceutical in the subject in the extended FOV is estimated based on the extension imaging data, and further based on a database (32) of reference subjects. The tomographic radioemission data are reconstructed to generate a reconstructed image (26) of the subject in the imaging FOV. The reconstruction includes correcting the reconstructed image for scatter from the extended FOV into the imaging FOV based on the estimated distribution of the radiopharmaceutical in the subject in the extended FOV.
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公开(公告)号：US10852448B2
公开(公告)日：2020-12-01
申请号：US16469605
申请日：2017-12-06
发明人： Xiyun Song , Chuanyong Bai , Andriy Andreyev , Bin Zhang , Shushen Lin , Jinghan Ye , Michael Allen Miller , Zhiqiang Hu
摘要： A PET detector array (8) comprising detector pixels acquires PET detection counts along lines of response (LORs). The counts are reconstructed to generate a reconstructed PET image (36, 46). The reconstructing is corrected for missing LORs which are missing due to dead detector pixels of the PET detector array. The correction may be by estimating counts along the missing LORs (60) by interpolating counts along LORs (66) neighboring the missing LORs. The interpolation may be iterative to handle contiguous groups of missing detector pixels. The correction may be by computing a sensitivity matrix having matrix elements corresponding to image elements (80, 82) of the reconstructed PET image. In this case, each matrix element is computed as a summation over all LORs intersecting the corresponding image element excepting the missing LORs. The computed sensitivity matrix is used in the reconstructing.
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公开(公告)号：US12131410B2
公开(公告)日：2024-10-29
申请号：US17293958
申请日：2019-11-15
CPC分类号： G06T11/008 , A61B6/037 , G06T11/006 , G06T2211/424
摘要： A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an imaging method (100). The method includes: receiving imaging data on a frame by frame basis for frames along an axial direction with neighboring frames overlapping along the axial direction wherein the frames include at least a volume (k) and a succeeding volume (k+1) at least partially overlapping the volume (k) along the axial direction; and generating an image of the volume (k) using an iterative image reconstruction process in which an iteration of the iterative image reconstruction process includes: computing a local penalty function for suppressing noise over the volume (k) including reducing the value of the local penalty function in an overlap region; generating an update image of the volume (k) using imaging data from the volume (k) and further using the local penalty function.
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公开(公告)号：US11877882B2
公开(公告)日：2024-01-23
申请号：US16605867
申请日：2018-04-17
发明人： Kushal Shah , Andriy Andreyev , Shushen Lin , Bin Zhang , Chuanyong Bai
IPC分类号： A61B6/00 , A61B6/03 , A61B5/1455
CPC分类号： A61B6/5288 , A61B6/037 , A61B6/461 , A61B6/527 , A61B6/5217 , A61B6/582 , A61B5/14552
摘要： A device (10) for measuring respiration of a patient includes a positron emission tomography (PET) or single photon emission computed tomography (SPECT) imaging device (12). At least one electronic processor (16) is programmed to: extract a first respiration data signal (32) from emission imaging data of a patient acquired by the PET or SPECT imaging device; extract a second respiration data signal (36) from a photoplethysmograph (PPG) signal of the patient; and combine the first and second extracted respiration data signals to generate a respiration signal (40) indicative of respiration of the patient.
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公开(公告)号：US11428829B2
公开(公告)日：2022-08-30
申请号：US16963320
申请日：2019-01-30
发明人： Xiyun Song , Chuanyong Bai , Jinghan Ye , Andriy Andreyev , Zhiqiang Hu
摘要： A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100) to reconstruct list mode data acquired over a frame acquisition time using a plurality of radiation detectors (17) in which the events of the list mode data is timestamped. The method includes: for the sub-frame bins of a plurality of sub-frame bins into which the frame acquisition time is divided, determining a sub-frame singles rates map for the plurality of radiation detectors from the list mode data whose time stamps reside in the sub-frame bin; determining a singles rate for the singles events of the list mode data using the sub-frame singles rates maps wherein the singles rates for the singles events are determined at a temporal resolution that is finer than the frame acquisition time; determining correction factors for the list mode data using the determined singles rates for the singles events of the list mode data; and reconstructing the list mode data of the frame acquisition time using the determined correction factors to generate a reconstructed image for the frame acquisition time.
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