公开(公告)号：US11009615B2

公开(公告)日：2021-05-18

申请号：US16470730

申请日：2017-12-18

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Chuanyong Bai ,  Andriy Andreyev ,  Andre Frank Salomon ,  Andreas Goedicke ,  Jinghan Ye ,  Yu-Lung Hsieh ,  Bin Zhang ,  Xiyun Song ,  Manoj Narayanan ,  Zhiqiang Hu

IPC: G01T1/00 ,  G01T1/29

Abstract: A time of flight (TOF) positron emission tomography (PET) image (38) is generated from TOF PET imaging data (10) acquired of a subject using a TOF PET imaging data acquisition device (6). Iterative image reconstruction (30) of the TOF PET imaging data is performed with TOF localization of counts along respective lines of response (LORs) to iteratively update a reconstructed image (32). Values for at least one regularization or filtering parameter are assigned to the TOF PET imaging data or to voxels of the reconstructed image based on an estimated TOF localization resolution for the TOF PET imaging data or voxels. Regularization (34) or filtering (36) of the reconstructed image is performed using the assigned values for the at least one regularization or filtering parameter. In some embodiments, the varying TOF localization resolution for the TOF PET imaging data or voxels is estimated based on related acquisition characteristics such as count rates or operating temperature of the detectors.

公开(公告)号：US10925554B2

公开(公告)日：2021-02-23

申请号：US15533749

申请日：2015-12-03

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Andriy Andreyev ,  Manoj Narayanan ,  Bin Zhang ,  Zhiqiang Hu ,  Yu-Lung Hsieh ,  Xiyun Song ,  Jinghan Ye

IPC: A61B6/00 ,  A61B6/03 ,  G06T11/00 ,  G01T1/16 ,  A61B5/00 ,  A61B5/055

Abstract: A radioemission scanner (12) is operated to acquire tomographic radioemission data of a radiopharmaceutical in a subject in an imaging field of view (FOV). An imaging system is operated to acquire extension imaging data of the subject in an extended FOV disposed outside of and adjacent the imaging FOV along an axial direction (18). A distribution of the radiopharmaceutical in the subject in the extended FOV is estimated based on the extension imaging data, and further based on a database (32) of reference subjects. The tomographic radioemission data are reconstructed to generate a reconstructed image (26) of the subject in the imaging FOV. The reconstruction includes correcting the reconstructed image for scatter from the extended FOV into the imaging FOV based on the estimated distribution of the radiopharmaceutical in the subject in the extended FOV.

公开(公告)号：US09474501B2

公开(公告)日：2016-10-25

申请号：US14911472

申请日：2014-08-07

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Amy Perkins ,  Manoj Narayanan ,  Andreia Maria Araujo Trindade Rodrigues ,  Pedro Jorge Da Silva Rodrigues

IPC: A61B6/03 ,  A61B6/02 ,  A61B6/00 ,  G01T1/29

CPC classification number: A61B6/583 ,  A61B6/037 ,  G01T1/2985

Abstract: A medical system (28) for normalization correction of an imaging system (10) includes a detector geometry correction unit (44), a crystal efficiency unit (46), and a normalization unit (54). The detector geometry correction unit (44) mathematically calculates a detector geometry correction component for a type of scanner (12) of interest. The crystal efficiency unit (46) configured to empirically determine a crystal efficiency component for at least one individual scanner (12). The normalization unit (54) generates a normalization data set (56) which corresponds to a normalization correction factor of the at least one individual scanner (12) in accordance with the detector geometry correction component and the crystal efficiency component.

Abstract translation: 用于成像系统（10）的归一化校正的医疗系统（28）包括检测器几何校正单元（44），晶体效率单元（46）和归一化单元（54）。 检测器几何校正单元（44）在数学上计算一种感兴趣的扫描仪（12）的检测器几何校正部件。 晶体效率单元（46）被配置为经验地确定至少一个单独的扫描器（12）的晶体效率分量。 归一化单元（54）根据检测器几何校正分量和晶体效率分量产生对应于至少一个单独扫描仪（12）的归一化校正因子的归一化数据组（56）。