公开(公告)号：US20220079550A1

公开(公告)日：2022-03-17

申请号：US17416874

申请日：2019-12-19

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Kevin Daniel Seng Hung LAU ,  Marco BARAGONA ,  Ralph Theodorus Hubertus MAESSEN ,  David PRATER

IPC: A61B8/04 ,  A61B8/02

Abstract: The invention provides a method for calculating an end-diastolic pressure-volume relationship. The method includes obtaining a cardiac input representing a region of interest, wherein the region of interest comprises a left ventricle and a left atrium of a subject. An end of diastasis volume of the left ventricle is then determined based on the cardiac input, wherein diastasis is a stage of diastole during a heart cycle before atrial contraction. Further, an end of diastasis pressure in the left atrium is determined based on the cardiac input and a linearized ventricular pressure-volume relationship is generated based on the end of diastasis volume of the left ventricle and the end of diastasis pressure in the left atrium. An end-diastolic pressure-volume relationship is then determined based on an end-diastolic volume of the left ventricle and the linearized ventricular pressure-volume relationship.