METHODS AND SYSTEMS FOR MODELING A CARDIAC SYSTEM

    公开(公告)号:US20220370140A1

    公开(公告)日:2022-11-24

    申请号:US17761628

    申请日:2020-09-16

    Abstract: The invention provides a system for determining a real-time valve function of a subject. The system comprises a processing unit adapted to: obtain a numerical model of a cardiac system, the numerical model being a 0D numerical model or a 1D numerical model, wherein the numerical model is adapted to receive physiological data as an input and output a simulated function of the cardiac system in real-time, wherein the simulated function of the cardiac system comprises a simulated function of a valve within the cardiac system. The processor is further adapted to obtain a continuous stream of physiological data from the subject; provide the continuous stream of physiological data as an input to the numerical model of the cardiac system, thereby generating a simulated real-time function of the cardiac system of the subject; and determine a real-time valve function of the subject based on the simulated real-time function of the cardiac system of the subject.

    METHODS AND SYSTEMS FOR MONITORING A FUNCTION OF A HEART

    公开(公告)号:US20220079550A1

    公开(公告)日:2022-03-17

    申请号:US17416874

    申请日:2019-12-19

    Abstract: The invention provides a method for calculating an end-diastolic pressure-volume relationship. The method includes obtaining a cardiac input representing a region of interest, wherein the region of interest comprises a left ventricle and a left atrium of a subject. An end of diastasis volume of the left ventricle is then determined based on the cardiac input, wherein diastasis is a stage of diastole during a heart cycle before atrial contraction. Further, an end of diastasis pressure in the left atrium is determined based on the cardiac input and a linearized ventricular pressure-volume relationship is generated based on the end of diastasis volume of the left ventricle and the end of diastasis pressure in the left atrium. An end-diastolic pressure-volume relationship is then determined based on an end-diastolic volume of the left ventricle and the linearized ventricular pressure-volume relationship.

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