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1.发明申请Multi-foci sonications for hyperthermia treatments using magnetic resonance-guided focused ultrasound 审中-公开使用磁共振引导聚焦超声治疗高热治疗的多灶超声公开(公告)号：US20150258353A1
公开(公告)日：2015-09-17
申请号：US14433468
申请日：2013-09-30
CPC分类号： A61N7/02 , A61B5/015 , A61B5/055 , A61B5/4839 , A61B5/7278 , A61B5/742 , A61B5/7475 , A61B2017/00084 , A61B2034/101 , A61B2090/374 , A61B2576/00 , A61M37/0092 , A61M2037/0007 , A61N2007/0078 , A61N2007/027
摘要： A mild hyperthermia treatment apparatus (10) includes an imager (12), which generates a planning image (34) and temperature maps (36) of a target region. An array of ultrasonic transducer drivers (52) individually drives ultrasonic transducers of a phased array of ultrasonic transducers (50). One or more processors or units receive a target temperature profile, and calculate power, frequency, and relative phase for the transducer drivers to drive the phased array of ultrasonic transducers to generate a multi-foci sonication pattern configured to heat the target region with the target temperature profile while limiting peak acoustic pressures. During treatment, the imager generates a series of temperature maps which the one or more processors or units compare with the target temperature profile and, based on the comparison, adjust the power, frequency and relative phase with which the transducer drivers drive the ultrasonic transducers.
摘要翻译： 温和的热疗治疗装置（10）包括成像器（12），其生成目标区域的计划图像（34）和温度图（36）。 超声换能器驱动器（52）的阵列分别驱动超声换能器（50）的相控阵列的超声换能器。 一个或多个处理器或单元接收目标温度分布，并且计算换能器驱动器的功率，频率和相对相位，以驱动超声换能器的相控阵列，以产生配置成与目标区域加热目标区域的多灶超声处理模式 温度曲线，同时限制峰值声压。 在处理期间，成像器产生一系列温度图，一个或多个处理器或单元与目标温度分布比较，并且基于比较，调整换能器驱动器驱动超声波换能器的功率，频率和相对相位。
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公开(公告)号：US20150005756A1
公开(公告)日：2015-01-01
申请号：US14241552
申请日：2012-09-26
IPC分类号： A61B18/04
CPC分类号： A61B18/04 , A61B5/055 , A61B17/2256 , A61B2017/00084 , A61B2018/00577 , A61B2018/00648 , A61B2018/00982 , A61B2090/374 , A61N7/02 , A61N2007/0065 , A61N2007/0078 , A61N2007/0091 , A61N2007/0095 , F04C2270/041 , G01R33/4804 , G01R33/4814
摘要： A medical apparatus (600, 700, 800, 900) comprising a high intensity focused ultrasound system (602) configured for generating focused ultrasonic energy (612) for sonicating within a target volume (620) of a subject (601). The high intensity focused ultrasound comprises an ultrasonic transducer (606) with a controllable focus (618). The apparatus further comprises a memory (634) containing machine executable for controlling the medical apparatus and a processor (628) for executing the instructions. Execution of the instructions causes the processor to cause (100, 200, 300, 400, 502) ultrasonic cavitations at multiple cavitation locations (622, 1002) within the target volume using the high intensity focused ultrasound system. Execution of the instructions further cause the processor to sonicate (102, 206, 306, 402, 504) multiple sonication locations (1004) within the target volume using the high intensity focused ultrasound system. The multiple sonication locations and the multiple cavitation locations are targeted by adjusting the controllable focus.
摘要翻译： 一种医疗设备（600,700,800,900），包括被配置用于产生聚焦超声波能量（612）的高强度聚焦超声系统（602），用于在受试者（601）的目标体积（620）内超声波处理。 高强度聚焦超声波包括具有可控焦距（618）的超声换能器（606）。 该装置还包括一个包含用于控制医疗装置的可执行机器的存储器（634）和用于执行指令的处理器（628）。 指令的执行导致处理器使用高强度聚焦超声系统在目标体积内的多个气蚀位置（622,1002）处引起（100,200,300,400,502）超声空穴。 执行指令还使得处理器使用高强度聚焦超声系统来超声波处理目标体积内的多个超声处理位置（1004）（102,206,306,402,504）。 多个超声处理位置和多个气穴位置是通过调节可控焦点来实现的。
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公开(公告)号：US11426604B2
公开(公告)日：2022-08-30
申请号：US16322671
申请日：2017-08-07
IPC分类号： A61N5/10 , A61B5/055 , G01R33/341 , G01R33/48
摘要： It is an object of the invention to address the above mentioned issues related to image quality and patient positioning. This object is achieved by a mock-up antenna configured to be used during radiation treatment delivery, wherein the radiation treatment is delivered based on a radiation treatment plan and wherein the radiation treatment plan is at least partly based on a planning magnetic resonance image. The mock-up antenna is substantially transparent to radiation and comprises connection means configured to allow a connection between the mock up antenna and a fixation means, which fixation means is configured to fixate a position of the mock-up antenna during radiation treatment and. The mock-up antenna further comprises an inner surface configured to be positioned towards a patient in a way such that is affects a position and/or orientation of the patient during radiation treatment delivery, wherein the inner surface has a shape substantially similar to a shape of a working magnetic resonance imaging antenna used during an acquisition of the planning magnetic resonance image.
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公开(公告)号：US10271890B2
公开(公告)日：2019-04-30
申请号：US14241552
申请日：2012-09-26
IPC分类号： A61B18/04 , A61N7/02 , G01R33/48 , A61B17/225 , A61N7/00 , A61B5/055 , A61B17/00 , A61B18/00 , A61B90/00
摘要： A medical apparatus (600, 700, 800, 900) including a high intensity focused ultrasound system (602) generates focused ultrasonic energy (612) for sonicating within a target volume (620) of a subject (601). The high intensity focused ultrasound includes an ultrasonic transducer (606) with a controllable focus (618). The apparatus further includes a memory (634) containing machine executable for controlling the medical apparatus and a processor (628). The processor causes (100, 200, 300, 400, 502) ultrasonic cavitations at multiple cavitation locations (622, 1002) within the target volume using the high intensity focused ultrasound system, and sonicates (102, 206, 306, 402, 504) multiple sonication locations (1004) within the target volume using the high intensity focused ultrasound system. The multiple sonication locations and the multiple cavitation locations are targeted by adjusting the controllable focus.
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