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1.发明授权公开(公告)号：US10976398B2
公开(公告)日：2021-04-13
申请号：US15501031
申请日：2015-08-11
发明人： Tim Nielsen , Sascha Krueger
IPC分类号： G01R33/567 , A61B5/113 , G01R33/565 , A61B5/00 , A61B5/055
摘要： A magnetic resonance imaging system connectable to a respiration monitor configured to provide an output signal whose level represents a respiration state. A prospective acquisition scheme for acquiring magnetic resonance images at each of a set of selected respiration states is provided, the triggering on the selected respiration states being based on predetermined threshold output signal levels of the respiration monitoring means, Respiration states at which magnetic resonance images were actually acquired, are compared with the selected respiration states according to the prospective acquisition scheme and predetermined ranges of tolerance of the selected respiration states, The prospective acquisition scheme is modified, if one of the actual respiration states lies outside the predetermined range of tolerance of the selected respiration state, and magnetic resonance imaging acquisition is executed pursuant to the modified prospective acquisition scheme.
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公开(公告)号：US10509090B2
公开(公告)日：2019-12-17
申请号：US15548213
申请日：2016-02-05
发明人： Sascha Krueger , Tim Nielsen
IPC分类号： G01R33/565 , G01R33/56 , G01R33/54 , A61B5/055 , G01R33/563 , G01R33/48 , A61N5/10
摘要： The invention provides for a method of operating a magnetic resonance imaging system. The method comprises the steps of: acquiring (200) first magnetic resonance data (142) by controlling the magnetic resonance imaging system with pulse sequence instructions (140), reconstructing (202) one or more first image (144) from the first magnetic resonance data, and assigning (204) the one or more first image to a first memory group of a set of memory groups (300). The method further comprises repeatedly performing the following steps: acquiring (206) sequential magnetic resonance data (148) by controlling the magnetic resonance imaging system with the pulse sequence instructions, reconstructing (208) one or more sequential image (150) from the sequential magnetic resonance data, computing (210) a distance measure (152) between the one or more sequential image and each of the set of memory groups, assigning (214) the one or more sequential images to a chosen memory group if the distance measure between the chosen group and the one or more sequential images is within a predetermined range, creating (216) a subsequent memory group (304) in the memory if the one or more sequential images is not assigned to the chosen memory group, and assigning (218) the one or more sequential image to the subsequent memory group if the subsequent memory group is created.
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公开(公告)号：US20230056449A1
公开(公告)日：2023-02-23
申请号：US17796685
申请日：2021-02-03
发明人： Tim Nielsen , Jan Jakob Meineke
IPC分类号： G01R33/56 , G01R33/561
摘要： Disclosed herein is a medical system (100, 300). The execution of machine executable instructions (120) causes a processor (104) to: receive (200) measured gradient echo k-space data (122); receive (202) an off-resonance phase map (124); reconstruct (204) an initial image (126) from the measured gradient echo k-space data; calculate (206) an upsampled phase map (128) from the off-resonance phase map; calculate (208) an upsampled image (130) from the initial image; calculating (210) a modulated image (132) by modulating the upsampled image with the upsampled phase map; calculate (212) a corrected image (134) comprising iteratively. The iterative calculation comprises: calculating (214) updated k-space data by applying a data consistency algorithm (138) to a k-space representation of the modulated image and the measured gradient echo k-space data and calculating (216) an updated image (142) from the updated k-space data. Calculation of the updated image comprises demodulation by the upsampled phase map and applying a smoothing algorithm.
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4.发明授权公开(公告)号：US10890638B2
公开(公告)日：2021-01-12
申请号：US16391457
申请日：2019-04-23
发明人： Juergen Rahmer , Tim Nielsen , Peter Boernert
IPC分类号： G01R33/385 , A61B5/055 , G01R33/44 , G01R33/48 , G01R33/483 , G01R33/561 , G01R33/58
摘要： A medical instrument includes a magnetic resonance (MR) imaging system with an imaging zone and a gradient coil system with three orthogonal gradient coils.
A processor controls the medical instrument to: repeatedly control the MR imaging system with calibration pulse sequence commands to acquire the MR calibration data for multiples slices using at least one of the three orthogonal gradient coils to generate the slice select gradient magnetic field; compute a Fourier transform of the MR calibration data for each of the voxels of the multiple slices in the phase encoding directions; compute an expansion of the Fourier transformed MR calibration data into spherical harmonics; and calculate a three-dimensional gradient impulse response function for the at least one of the three orthogonal gradient coils using the expansion into spherical harmonics. The calibration pulse sequence commands are configured to acquire MR calibration data from a phantom according to a calibration protocol with two-dimensional phase encoding perpendicular to a slice select gradient magnetic field.-
公开(公告)号：US10156623B2
公开(公告)日：2018-12-18
申请号：US14425669
申请日：2013-09-02
发明人： Tim Nielsen , Peter Börnert
IPC分类号： H03F1/26 , G01R33/565
摘要： A magnetic resonance imaging system (200, 300) acquires magnetic resonance data (242, 244). A processor (230) controls the magnetic resonance imaging system to execute instructions (250, 252, 254, 256, 258) which cause the processor to repeatedly: control (100) the magnetic resonance imaging system to acquire magnetic resonance data including magnetic resonance navigator data (244); create (102) a set of navigator vectors by extracting the navigator data from each portion of the magnetic resonance data; construct (104) a dissimilarity matrix (246, 400, 700, 800, 900, 1000, 1100, 1400, 1500) by calculating a metric between each of the set of navigator vectors; generate (106) a matrix classification (248) of the dissimilarity matrix using a classification algorithm; and control (108) the magnetic resonance imaging system to modify acquisition of the magnetic resonance data using the matrix classification.
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公开(公告)号：US20230394652A1
公开(公告)日：2023-12-07
申请号：US18031889
申请日：2021-10-11
发明人： Nicola Pezzotti , Christian Wuelker , Tim Nielsen , Karsten Sommer , Michael Grass , Heinrich Schulz , Sergey Kastryulin
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , G06T2207/20084 , G06T2207/20081
摘要： Disclosed herein is a medical system (100, 300, 400) comprising a memory (110) storing a trainable machine learning module (122) trained using training data descriptive of a training data distribution (600) to output a reconstructed medical image (136) in response to receiving measured medical image data (128) as input. The medical system comprises a computational system (104). The execution of machine executable instructions (120) causes the computational system to: receive (200) the measured medical image data and determine (202) the out-of-distribution score and the in-distribution accuracy score consecutively in an order determined a sequence, detect (204) a rejection of the measured medical image data using the out-of-distribution score and/or the in-distribution accuracy score during execution of the sequence, provide (206) a warning signal (134) if the rejection of the measured medical image data is detected. The out-of-distribution score is determined by inputting the measured medical image data into the out-of-distribution estimation module. The in-distribution accuracy score is determined by inputting the measured medical image data into the in-distribution accuracy estimation module.
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公开(公告)号：US11684801B2
公开(公告)日：2023-06-27
申请号：US16492186
申请日：2018-03-19
IPC分类号： A61N5/10
CPC分类号： A61N5/1037 , A61N5/1038 , A61N5/1049 , A61N2005/1055
摘要： For delivering an image-guided radiation therapy treatment to a moving structure included in a region of a patient body a series of first images of the region of the patient body in different phases of a motion of the structure is acquired in accordance with a first imaging mode. The series of first images is associated with a series of second images of the patient body in essentially the same phases of the motion of the target structure, the second images being acquired in a second imaging mode. During the treatment, a third image is acquired using the second imaging mode during the radiation therapy treatment and a continuation of the radiation therapy treatment is planned on the basis of data relating to one of the first images selected on the basis of a comparison between the third image and the second images associated with the first images.
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公开(公告)号：US09753111B2
公开(公告)日：2017-09-05
申请号：US14895319
申请日：2014-06-07
发明人： Peter Forthmann , Sascha Krueger , Tim Nielsen , Jurgen Erwin Rahmer , Peter Vernickel , Peter Boernert , Ulrich Katscher
IPC分类号： G06K9/00 , G01R33/54 , G01B11/24 , G01G19/44 , G01R33/30 , G06T7/00 , H04N5/225 , G06T7/73 , G01R33/28
CPC分类号： G01R33/543 , G01B11/24 , G01G19/44 , G01R33/28 , G01R33/307 , G06T7/0012 , G06T7/73 , G06T2200/04 , G06T2207/10088 , G06T2207/30196 , H04N5/225
摘要： A system and method determines an isocenter for an imaging scan. The method includes receiving, by a control panel, patient data generated by at least one sensor, the patient data corresponding to dimensions of a body of a patient. The method includes generating, by the control panel, model data as a function of the patient data, the model data representing the body of the patient. The method includes receiving, by the control panel, a target location on the model data, the target location corresponding to a desired position on the body of the patient for performing the imaging scan. The method includes determining, by the control panel, an isocenter for the imaging scan as a function of the target location.
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公开(公告)号：US20230258750A1
公开(公告)日：2023-08-17
申请号：US18014563
申请日：2021-06-22
CPC分类号： G01R33/3692 , G01R33/583 , G01R33/3607
摘要： A method of setting an RF operating frequency of an MRI system (1) uses a first reference frequency signal, obtained from a geo-satellite positioning system, as a stable long term frequency reference. A second frequency source (24) is calibrated using the first frequency reference signal and the second frequency reference source (24) is then used as the master clock for the MRI system (1), for setting the RF operating frequency.
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公开(公告)号：US11609294B2
公开(公告)日：2023-03-21
申请号：US16479802
申请日：2018-01-23
发明人： Falk Uhlemann , Tim Nielsen , Jan Hendrik Wuelbern
IPC分类号： G01R33/56 , G01R33/563 , G01R33/567 , A61B5/055 , A61B5/00
摘要： The invention provides for a magnetic resonance imaging system (100, 200) comprising a memory (148) for storing machine executable instructions (150) and pulse sequence commands (152). The pulse sequence commands are configured for acquiring a four dimensional magnetic resonance data set (162) from an imaging region of interest (109). The four dimensional magnetic resonance data set is at least divided into three dimensional data magnetic resonance data sets (400, 402, 404, 406, 408) indexed by a repetitive motion phase of the subject. The three dimensional data magnetic resonance data sets are further at least divided into and indexed by k-space portions (410, 412, 414, 416, 418, 420, 422, 424, 426, 428, 430, 432, 434, 436). The magnetic resonance imaging system further comprises a processor (144) for controlling the magnetic resonance imaging system. Execution of the machine executable instructions causes the processor during a first operational portion (310) to iteratively: receive (300) a motion signal (156) descriptive of the repetitive motion phase; acquire (302) an initial k-space portion using the pulse sequence commands, wherein the initial k-space portion is selected from the k-space portions; store (304) the motion signal and the initial k-space portion in a buffer (158) for each iteration of the first operational portion; at least partially construct (306) a motion phase mapping (160) between the motion signal and the repetitive motion phase; and continue (308) the first operational portion until the motion phase mapping is complete. Execution of the machine executable instructions causes the processor to assign (312) the initial k-space portion for each iteration of the first operational portion in the temporary buffer to the four dimensional magnetic resonance data set using the motion phase mapping. Execution of the machine executable instructions causes the processor during a second operational portion (332) to iteratively: receive (314) the motion signal; determine (316) a predicted next motion phase using the motion signal and the motion phase mapping; select (318) a subsequent k-space portion (154) from the k-space portions of the four dimensional magnetic resonance data set using the predicted next motion phase; acquire (320) the subsequent k-space portion using the pulse sequence commands; rereceive (322) the motion signal; determine (324) a current motion phase using the re-received motion signal and the motion phase mapping; assign (326) the subsequent k-space portion to the four dimensional magnetic resonance data set using the current motion phase; and repeat (328) the second operational portion until the k-space portions for each repetitive motion phase has been assigned.
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