专利检索 ap:("KOREA INSTITUTE OF GEOSCIENCE AND MINERAL RESOURCES") AND inv:"Jae Hwan Kim" 第 1 页

1.

发明授权
Method for synthesizing high-purity montmorillonite 有权

公开(公告)号：US10758564B2

公开(公告)日：2020-09-01

申请号：US16158390

申请日：2018-10-12

申请人： KOREA INSTITUTE OF GEOSCIENCE AND MINERAL RESOURCES

发明人： Sung Man Seo , Il Mo Kang , Ki Min Roh , Dae Young Kim , Jae Hwan Kim

IPC分类号： A61K8/26 , A61K33/06 , A61Q19/00 , C01B33/26 , C01B33/40

摘要： A method for synthesizing high purity montmorillonite is disclosed. According to this synthesis method, bentonite is dissolved in aqua regia to produce a solution and then sodium hydroxide (NaOH) is added to the solution to produce a mixed solution. Then, the mixed solution is kept in a sealed state at a temperature of 90° C. inclusive to 100° C. exclusive to synthesize montmorillonite crystals.

2.

发明申请
DRUG AND LAYERED SILICATE COMPOSITE WITH IMPROVED ORAL BIOAVAILABILITY, ORAL PHARMACOLOGICAL COMPOSITION CONTAINING THE COMPOSITE AND METHOD FOR PRODUCING THE COMPOSITE 审中-公开

公开(公告)号：US20190274963A1

公开(公告)日：2019-09-12

申请号：US16295051

申请日：2019-03-07

申请人： KOREA INSTITUTE OF GEOSCIENCE AND MINERAL RESOURCES

发明人： Il Mo Kang , Dae Duk Kim , Ju Hwan Park , Ki Min Roh , Jangik Ike Lee , Jae Hwan Kim , Sung Man Seo , Su Young Jung

IPC分类号： A61K9/48 , A61K31/44 , A61K9/19

摘要： A drug and layered silicate composite is provided. The drug and layered silicate contains layered silicate powders; and a drug compound bound to between layers of the silicate powders, wherein the drug compound is present in an amorphous state in the composite. Using such a composite may significantly improve absorption and bioavailability of a sorafenib compound.