公开(公告)号：US20240158411A1

公开(公告)日：2024-05-16

申请号：US18565799

申请日：2021-12-09

Applicant: KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY

Inventor： Hee Jae SHIN ,  Byeoung Kyu CHOI ,  Hwa Sun LEE

IPC: C07D493/04 ,  A61P35/00

CPC classification number: C07D493/04 ,  A61P35/00 ,  C07B2200/07

Abstract: The present invention relates to a novel xanthone compound, an optical isomer thereof or a pharmaceutically acceptable salt thereof that exhibits cytotoxicity against cancer cell lines and inhibits cancer cell growth, thereby exhibiting excellent preventive or therapeutic effects on various cancer cells.

公开(公告)号：US20220033413A1

公开(公告)日：2022-02-03

申请号：US17274988

申请日：2019-06-03

Applicant: KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY

Inventor： Hee Jae SHIN ,  Byeoung Kyu CHOI ,  Hwa Sun LEE ,  Hyi Seung LEE ,  Yeon Ju LEE ,  Jong Seok LEE ,  Ji Hoon LEE

IPC: C07D493/16

Abstract: The present invention relates to new compounds derived from marine actinomycetes Streptomyces, and the new compound according to the present invention has an inhibitory effect of NO production on BV-2 microglia stimulated with LPS, and thus can be utilized for the prevention and treatment of neuroinflammatory diseases.