公开(公告)号：US10709754B2

公开(公告)日：2020-07-14

申请号：US16086672

申请日：2017-04-07

Applicant: KOREA INSTITUTE OF ORIENTAL MEDICINE

Inventor： Dong Seon Kim ,  Ohn Soon Kim ,  Yun Mi Lee ,  Young-Sil Lee ,  Eun Jung Son

IPC: A61K36/9068 ,  A61K36/9062 ,  A23L33/105 ,  A61P19/06 ,  A61K45/06

Abstract: The present invention relates to a composition for preventing, ameliorating, or treating hyperuricemia or metabolic disorders related with hyperuricemia comprising an extract of Alpinia oxyphylla as an effective ingredient. Because the extract of Alpinia oxyphylla of the present invention can reduce the uric acid amount in blood of an animal model and is derived from natural products, and the raw materials can be easily obtained, it can be widely used in industries that are related to hyperuricemia or metabolic disorders related with hyperuricemia. It can be effectively used for prevention, amelioration, or treatment of gout or gouty arthritis, in particular.

公开(公告)号：US10098921B2

公开(公告)日：2018-10-16

申请号：US15539239

申请日：2015-12-18

Applicant: KOREA INSTITUTE OF ORIENTAL MEDICINE

Inventor： Dong Seon Kim

IPC: A61K36/28 ,  A61K36/54 ,  A61K36/287 ,  A23L33/105 ,  A61P19/06 ,  A61P19/02

Abstract: An anti-gout composition including the mixed extract of Chrysanthemum indicum and Cinnamomum cassia as an active ingredient shows substantially greater inhibitory effects on xanthine oxidase than when Chrysanthemum indicum or Cinnamomum cassia is used separately. An animal model treated with the mixed extract of Chrysanthemum indicum and Cinnamomum cassia experienced a decrease in uric acid in serum and in urine. The mixed extract of Chrysanthemum indicum and Cinnamomum cassia is an active ingredient induced from a natural material, and, accordingly, the mixed extract is safe and a source material therefor is easily provided. Accordingly, the mixed extract can be widely used in gout-related industries.